Resistencias de Mycobacterium tuberculosis en el área del Hospital de Sagunto desde 1999 al 2004

Galindo, Mireia; Mira, Áurea; Contell, A. Albert; Sanchis, B Serra; Quiles, Ismael; Fornells, Jaime; Trullenque, Ramón; González, Carmen

doi:10.1157/13090504

Cited by 5 publications

(1 citation statement)

References 15 publications

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“…Although we failed to read the full text of these studies, associations between smoking and drug resistance could be discerned from the abstract of a study published in Russian, 60 and another in Spanish. 61 Second, we included data from different study designs, which may have led to the heterogeneity of the results. However, the similar positive association detected between smoking and DR-TB in cohort study subgroups, which are more liable to prove a cause-and-effect relationship than case–control and cross-sectional studies, reinforces our conclusion.…”

Section: Discussionmentioning

confidence: 99%

Association between tobacco smoking and drug-resistant tuberculosis

Wang

Huang

Wang

et al. 2018

IDR

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BackgroundTobacco smoking is a risk factor for tuberculosis but little is known about the relationship between tobacco smoking and drug-resistant tuberculosis (DR-TB). We undertook a systematic review and meta-analysis to quantitatively assess the association between DR-TB and tobacco smoking.MethodsWe searched for relevant studies in the Ovid MEDLINE, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, WANFANG, and WEIPU data-bases from inception to September 1, 2017. Results were expressed as odds ratios (ORs) with accompanying 95% CIs, and subgroup analyses were performed by study design, smoking type, DR-TB type, and multivariate analysis.ResultsThirty-three studies related to tobacco smoking and DR-TB were included. We found substantial evidence that tobacco smoking is associated with an increased risk of DR-TB (OR 1.57, 95% CI 1.33–1.86). Associations were also found in subgroup analyses: for multidrug-resistant tuberculosis (OR 1.49, 95% CI 1.19–1.86) and for any DR-TB (OR 1.70, 95% CI 1.3–2.23); the pooled OR was 1.45 (95% CI 1.11–1.90) for current smoking, 2.25 (95% CI 1.46–3.47) for past smoking, and 1.56 (95% CI 1.22–1.98) for smoking history; and similar ORs were also observed in study design and multivariate analysis subgroup analysis.ConclusionThis study demonstrated that tobacco smoking is an independent risk factor for DR-TB.

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Section: Discussionmentioning

confidence: 99%