Resistencia antibiótica y distribución de serotipos en cepas neumocócicas invasivas en adultos hospitalizados en Lima, Perú

Gómez, Juan Carlos Castro; Siccha, Sofía M; Egoavil, Martha; Chaparro, Eduardo; Hernandez, Roger; Silva, Wilda; Águila, Olguita del; Saenz, A.; Campos, Francisco; Reyes, Isabel Urbano; Castillo, María E.; Ochoa, Theresa J.

doi:10.17843/rpmesp.2017.344.2884

Cited by 6 publications

(8 citation statements)

References 24 publications

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“…* [ 45 ] ; ^ [ 46 ] ; > [ 47 ] ; # estimated from accumulated yearly vaccinations. National Data Sources: Most data from World Health Organization (WHO), immunization, vaccines, and biologicals, https://www.who.int/immunization/monitoring_surveillance/data/en/; additional data for individual countries, especially for pneumococcal vaccination rates among adults and for influenza vaccination rates: Austria [ 48 ] ; Australia [ 49–51 ] ; Canada [ 52,53 ] ; France [ 54 ] ; Germany [ 55,56 ] ; Greece [ 57 ] ; Hong Kong [ 49,58 ] ; Ireland [ 59 ] ; Israel [ 60 ] ; Italy [ 19,61–63 ] ; Japan [ 64–68 ] ; Mexico [ 69 ] ; The Netherlands [ 70 ] ; Portugal [ 71 ] ; South Korea [ 72–76 ] ; Spain [ 19,42,43 ] ; Switzerland [ 77 ] ; United Kingdom [ 78 ] ; United States [ 79–84 ] ; Brazil [ 85–87 ] ; Chile [ 86,88 ] ; Peru [ 86,88–90 ] .…”

Section: Evidence For the Hypothesesmentioning

confidence: 99%

“…[ 42,43 ] Belgium similarly saw a reemergence of pneumonia deaths involving previously herd‐immunized strains of S. pneumoniae after switching from PCV13 to PCV7. [ 44 ] Most South American nations have also relied upon PCV7 or PCV10, [ 85–90 ] joining Italy, Spain, and Belgium in lacking the protection against COVID‐19 infection hypothesized here. All have seen unusually high COVID‐19 cases and deaths.…”

Section: Evidence For the Hypothesesmentioning

confidence: 99%

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Age and Location in Severity of COVID‐19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?

Root‐Bernstein

2020

BioEssays

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Two conundrums puzzle COVID-19 investigators: 1) morbidity and mortality is rare among infants and young children and 2) rates of morbidity and mortality exhibit large variances across nations, locales, and even within cities. It is found that the higher the rate of pneumococcal vaccination in a nation (or city) the lower the COVID-19 morbidity and mortality. Vaccination rates with Bacillus Calmette-Guerin, poliovirus, and other vaccines do not correlate with COVID-19 risks, nor do COVID-19 case or death rates correlate with number of people in the population with diabetes, obesity, or adults over 65. Infant protection may be due to maternal antibodies and antiviral proteins in milk such as lactoferrin that are known to protect against coronavirus infections. Subsequent protection might then be conferred (and correlate with) rates of Haemophilus influenzae type B (Hib) (universal in infants) and pneumococcal vaccination, the latter varying widely by geography among infants, at-risk adults, and the elderly. Also see the video abstract here https://youtu.be/GODBYRbPL00.

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Section: Evidence For the Hypothesesmentioning

confidence: 99%

Section: Evidence For the Hypothesesmentioning

confidence: 99%

Age and Location in Severity of COVID‐19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?

Root‐Bernstein

2020

BioEssays

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“…Although it is necessary to document the prevalence and possible resistance mechanisms of Mycoplasma pneumoniae and Chlamydia pneumoniae in Peru [ 46 ], the local rate of resistance to macrolides in Streptococcus pneumoniae strains obtained in hospitalized patients in Lima was higher than 30% [ 47 ]. Future studies are required to determine the role of antibiotics in inpatient COVID-19 care, as well as resistance rates, following the pandemic era.…”

Section: Discussionmentioning

confidence: 99%

Identification of Coinfections by Viral and Bacterial Pathogens in COVID-19 Hospitalized Patients in Peru: Molecular Diagnosis and Clinical Characteristics

et al. 2021

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The impact of respiratory coinfections in COVID-19 is still not well understood despite the growing evidence that consider coinfections greater than expected. A total of 295 patients older than 18 years of age, hospitalized with a confirmed diagnosis of moderate/severe pneumonia due to SARS-CoV-2 infection (according to definitions established by the Ministry of Health of Peru) were enrolled during the study period. A coinfection with one or more respiratory pathogens was detected in 154 (52.2%) patients at hospital admission. The most common coinfections were Mycoplasma pneumoniae (28.1%), Chlamydia pneumoniae (8.8%) and with both bacteria (11.5%); followed by Adenovirus (1.7%), Mycoplasma pneumoniae/Adenovirus (0.7%), Chlamydia pneumoniae/Adenovirus (0.7%), RSV-B/Chlamydia pneumoniae (0.3%) and Mycoplasma pneumoniae/Chlamydia pneumoniae/Adenovirus (0.3%). Expectoration was less frequent in coinfected individuals compared to non-coinfected (5.8% vs. 12.8%). Sepsis was more frequent among coinfected patients than non-coinfected individuals (33.1% vs. 20.6%) and 41% of the patients who received macrolides empirically were PCR-positive for Mycoplasma pneumoniae and Chlamydia pneumoniae.

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“…Las enfermedades asociadas fueron coincidentes con las de Villena, quien concluyó que la dm y las enfermedades cardiovasculares son los principales motivos de hospitalización, asociados fundamentalmente cona infecciones (15 (16,17). En este contexto, en la hipertensión arterial, los órganos más afectados son corazón, riñones y cerebro (18).…”

Section: Discussionunclassified

Estudio de prescripción-indicación en pacientes con antimicrobianos de amplio espectro en medicina interna de un hospital de Ecuador

Viamonte

Martínez²

2019

Rev. Cienc. salud

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Introducción: desde hace varios años existe preocupación por el incremento específico en el consumo de antimicrobianos por los problemas que estos generan; por tal motivo, se decidió diseñar un programa de atención farmacéutica en pacientes hospitalizados en servicios abiertos para evitar el desarrollo de problemas relacionados con medicamentos asociados con antimicrobianos. Materiales y métodos: se realizó un estudio retrospectivo de utilización de medicamentos, del tipo prescripción-indicación en una muestra de estudio de 25 pacientes que recibieron antimicrobianos de amplio espectro en el área de medicina interna del hospital José María Velasco Ibarra desde abril hasta julio del 2016. Resultados: el 76 % de los pacientes fueron mujeres. La patología más frecuente que requirió la utilización de antimicrobianos fue la infección de vías urinarias complicada (48 %): el 24 % de los pacientes recibió más de un antibiótico de amplio espectro y el más utilizado fue el imipenem/cilastatina (34.4 %), seguido de la piperacilina/tazobactam y el cefepime, ambas con un 28.1% y la vancomicina (9.4%). El 48% de las prescripciones fueron inadecuadas, se detectó la presencia de PRM en el 84 % de los pacientes. Conclusión: el diseño de un programa de atención farmacéutica en pacientes hospitalizados garantiza la identificación, prevención y/o solución de los problemas relacionados con medicamentos, su uso adecuado y la calidad de la atención.

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Resistencia antibiótica y distribución de serotipos en cepas neumocócicas invasivas en adultos hospitalizados en Lima, Perú

Cited by 6 publications

References 24 publications

Age and Location in Severity of COVID‐19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?

Age and Location in Severity of COVID‐19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?

Identification of Coinfections by Viral and Bacterial Pathogens in COVID-19 Hospitalized Patients in Peru: Molecular Diagnosis and Clinical Characteristics

Estudio de prescripción-indicación en pacientes con antimicrobianos de amplio espectro en medicina interna de un hospital de Ecuador

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