Resistencia Antibiótica de Enterobacterias Aisladas de Monos (Ateles, Callicebus y Lagothrix) en Semicautiverio en un Centro de Rescate, Perú

Abstract

RESUMENEl Perú cuenta con diversos géneros y especies de primates no humanos, dentro de los que se encuentran las especies Ateles belzebuth, Ateles chamek, Callicebus oenanthe, Lagothrix cana y Lagothrix lagotricha cuyos estados de conservación según la Lista Roja de la UICN se encuentran en la categoría amenazada. El objetivo del presente estudio fue determinar el perfil de resistencia antibacteriana de cepas entéricas aisladas de Ateles, Callicebus y Lagothrix en semicautiverio en un centro de rescate, Perú. La toma de muestras se realizó por hisopado rectal en 56 primates no humanos habitantes del Centro de Rescate y Rehabilitación de Primates Ikama Peru. El aislamiento e identificación bacteriana se realizó mediante un protocolo estándar, y la sensibilidad bacteriana mediante la técnica de Kirby-Bauer. Se aislaron 106 cepas bacterianas de la familia Enterobacteriaceae. La especie de mayor prevalencia fue Escherichia coli con 42.5% (45/106). Los aislados mostraron mayor grado de resistencia a cefalotina (46.2%), amoxicilinaácido clavulánico (31.1%), tobramicina (30.2%) y tetraciclina (24.5%).Palabras clave: enterobacterias, monos, Ateles, Callicebus, Lagothrix, resistencia, antibióticos ABSTRACT Several genera and species of nonhuman primates can be found in Peru. Among them, Ateles belzebuth, Ateles chamek, Callicebus oenanthe, Lagothrix cana and Lagothrix lagotricha. These species according to the IUCN Red List are in the threatened category. The aim of this study was to determine the antibacterial sensitivity profile of

Antibiotic susceptibility among non-clinical Escherichia coli as a marker of antibiotic pressure in Peru (2009–2019): one health approach

“…Only 3 studies, one in Lima and the other two in the jungle area of Peru, reported data of susceptibility to antimicrobial agents in E. coli from wild animals [72,73,74] (Table 7).…”

“…Of note, while classified as "wild", only one study involved freeranging animals (Caiman cocodrilus) [73], while another 2 studies analyzed samples from animals living in captivity or semi-captivity [72,74]. Another study, including bats (Desmodus rotundus) was not considered because of the presence of selective bias [65].…”

“…e: Data about sampling or AMR may also be found inGomes et al, 2013, Gomes et al, 2019 Ochoa et al, 2009, and Pons et al, 2014[75,76,77,78]. f: Includes free wild animals[73] and wild animals living in captivity or in semi-captivity[72,74]. g: The article only reports isolates possessing ESBLs.…”

Diversity and prevalence of zoonotic infections at the animal-human interface of primate trafficking in Peru

“…were reported in 21% wild monkeys and 32% pet monkeys [ 58 ], while primate rescue centers in the same region report primates infected with antimicrobial-resistant enterobacteria such as Escherichia coli , Salmonella arizonae , Shigella sp ., and Serratia spp . [ 41 ]. Within the country, human-associated infections such as mycobacteria [ 59 ] and human herpesvirus type 1 [ 60 ] have been documented exclusively in captive primates, whereas a high seroprevalence of arbovirus antibodies has been observed solely in wild monkeys [ 61 , 62 ].…”

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“…Several studies report an increase in antimicrobial resistance and minimal sensitivity to different antibiotics to pathogenic microorganisms of Salmonella spp. and Escherichia coli in bird, pig, guinea pigs, bovine and silvestria animals such as monkeys, generating important losses of genetic and socioeconomic value in breeders (Oha, 2012;Medina et al, 2017;. There are no related studies on the use of antibiotics in veterinary against Salmonella spp.…”