Resistance trends and risk factors of extended spectrum β-lactamases in Escherichia coli infections in Aleppo, Syria

First report on class 1 integrons and Trimethoprim-resistance genes fromdfrAgroup in uropathogenicE. coli(UPEC) from the Aleppo area in Syria

“…Urine samples were collected from UTI patients during the study period in order to provide 104 unique isolates, which were studied to uncover antibiotic resistance phenotypes, as previously published by the current authors 6 . Out of the total number of tested isolates 75 (72.1%) were resistant to Trimethoprim, and only these were taken for further phenotypic and molecular investigations in this study.…”

The Mediterranean Region : A Reservoir for CTX - M - ESBL - Producing Enterobacteriacae

“…In a recent study, resistance to carbapenemase production was detected in ESBL E. coli and K. pneumoniae isolates (Baroud et al, 2013). There is a lack of sufficient information about the prevalence of ESBLs and their molecular characterization in Syria; however, in a recently published article, the high prevalence of ESBL producing E. coli was revealed reaching 52% among urinary tract infections patients (Al-Assil et al, 2013). In Jordan, the prevalence of ESBLs has been reported to be relatively high compared to other reported data worldwide (Youssef et al, 1999;Shehabia et al, 2000).…”

Factores clínicos asociados a multirresistencia bacteriana en un hospital de cuarto nivel

“…La exposición a quinolonas es un hallazgo consistente con otros estudios reportados en la literatura 8,13,14 , sin embargo, el trimetoprim/sulfametoxazol se ha reportado como factor protector en infecciones por E. coli multirresistente 10 o ha sido no significativo en cuanto a su asociación con el evento 4 . Este hallazgo puede deberse a la presencia de confusión con el antecedente de trasplante, pues el trimetoprim/sulfametoxazol es un tratamiento comúnmente usado en este tipo de pacientes.…”