Resistance training improves muscle strength and functional capacity in multiple sclerosis

Dalgas, Ulrik; Stenager, Egon; Jakobsen, Johannes; Petersen, Thor; Hansen, Hans J.; Knudsen, Christina Bruun; Overgaard, Kristian; Ingemann-Hansen, T

doi:10.1212/wnl.0b013e3181bf98b4

Cited by 226 publications

(260 citation statements)

References 22 publications

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“…Existing recommended levels for physical activity focuses on engaging in structured forms of exercise using moderate to vigorous activities [38,39]. Yet there is evidence to suggest that only 20% of pwMS met the public health guidance for physical activity (moderate to vigorous physical activity !5 days per week or vigorous activity 3 days per week) [40].…”

Section: Insights Into the Reasons Why Pwms Engage In Exercise And Phmentioning

confidence: 99%

Physical activity and exercise priorities in community dwelling people with multiple sclerosis: a Delphi study

Stennett

Souza

Norris

2017

Disability and Rehabilitation

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Aims: Exercise and physical activity have been found to be beneficial in managing disabilities caused by multiple sclerosis. Despite the known benefits, many people with multiple sclerosis are inactive. This study aimed to identify the prioritised exercise and physical activity practices of people with multiple sclerosis living in the community and the reasons why they are engaged in these activities. Methods: A four Round Delphi questionnaire scoped and determined consensus of priorities for the top 10 exercise and physical activities and the reasons why people with multiple sclerosis (n ¼ 101) are engaged in these activities. Data were analysed using content analysis, descriptive statistics, and nonparametric tests. Results: The top 10 exercise and physical activity practices and the top 10 reasons why people with multiple sclerosis (n ¼ 70) engaged in these activities were identified and prioritised. Consensus was achieved for the exercise and physical activities (W ¼ 0.744, p < .0001) and for the reasons they engaged in exercise and physical activity (W ¼ 0.723, p < .0001). Conclusion:The exercise and physical activity practices and the reasons people with multiple sclerosis engaged in exercise and physical activity were diverse. These self-selected activities and reasons highlighted that people with multiple sclerosis might conceptualise exercise and physical activity in ways that may not be fully appreciated or understood by health professionals. Considerations of the views of people with multiple sclerosis may be essential if the goal of increasing physical activity in this population is to be achieved. ä IMPLICATIONS FOR REHABILITATIONHealth professionals should work collaboratively with people with multiple sclerosis to understand how they prioritise activities, the underlying reasons for their prioritisations and embed these into rehabilitation programmes. Health professionals should utilise activities prioritised by people with multiple sclerosis in the community as a way to support, promote, and sustain exercise and physical activity in this population. Rehabilitation interventions should include both the activities people with multiple sclerosis prioritise and the reasons why they engage in exercise and physical activity as another option for increasing physical activity levels and reducing sedentary behaviours. ARTICLE HISTORY

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Section: Insights Into the Reasons Why Pwms Engage In Exercise And Phmentioning

confidence: 99%

Physical activity and exercise priorities in community dwelling people with multiple sclerosis: a Delphi study

Stennett

Souza

Norris

2017

Disability and Rehabilitation

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“…13,15 During the past two decades, however, research has identified several forms of exercise with physical, emotional, and psychological benefits to individuals with MS, including Pilates, [16][17][18][19] yoga, 10,12 aquatics, 19 endurance training, 3,20 strength and cardiorespiratory training, 21 walking, 22 aerobic exercise, 23 and resistance training. [24][25][26] Exercise is now considered to be well tolerated for individuals with MS and is commonly recommended for improved physical and emotional functioning. 3,14 For example, Guclu-Gunduz and colleagues 17 investigated the effects of an 8-week program of Pilates, a type of mind-body exercise, on balance, mobility, and strength among 26 ambulatory adults with MS.…”

Section: Benefits Of Exercisementioning

confidence: 99%

Therapeutic Yoga: Symptom Management for Multiple Sclerosis

Rogers

MacDonald

2015

The Journal of Alternative and Complementary Medicine

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Multiple sclerosis (MS) is the most common autoimmune inflammatory demyelinating disease of the central nervous system, affecting over 2.3 million people worldwide. According to the National Institute of Neurological Disorders and Stroke, the age of disease onset is typically between 20 and 40 years, with a higher incidence in women. Individuals with MS experience a wide range of symptoms, including declining physical, emotional, and psychological symptoms (e.g., fatigue, imbalance, spasticity, chronic pain, cognitive impairment, bladder and bowel dysfunction, visual and speech impairments, depression, sensory disturbance, and mobility impairment). To date, both the cause of and cure for MS remain unknown. In recent years, more individuals with MS have been pursuing alternative methods of treatment to manage symptoms of the disease, including mind-body therapies such as yoga, meditation, breathing, and relaxation techniques.It has been suggested that the practice of yoga may be a safe and effective way of managing symptoms of MS. Therefore, the purpose of this paper is to summarize the most relevant literature on exercise and mindbody modalities to treat MS symptoms and, more specifically, the benefits and potential role of yoga as an alternative treatment of symptom management for individuals with MS. The article also discusses future directions for research.

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“…Aerobic and combined aerobic and resistance training interventions have improved cardiorespiratory fitness along with beneficial changes in walking performance [46,47], spatiotemporal gait parameters [48], and symptomatic fatigue [46,47,[49][50][51] in persons with MS. For example, 8 weeks (3x/week) of moderate intensity leg cycling resulted in a significant increase in VO 2peak measured on a leg cycle ergometer, 6MW distance, and self-reported energy levels in 11 persons with MS who had moderate disability (mean EDSS=3.5) [46]. Exercise training interventions that primarily involved resistance training have improved muscular fitness, as well as walking performance [52][53][54][55][56], and symptomatic fatigue [49,51,55,57] in persons with MS. For example, significant improvements in knee flexor peak torque measured on a seated dynamometer, and T25FW and 500 MW performance were observed following 26 weeks of resistance (4x/ week) and aerobic training (1x/week) in 91 persons with MS who had a range of disability (EDSS range=1-5.5) [16]. There are some data suggesting that exercise training influences balance and body fatness as indicators of motor and morphological domains of fitness, and such changes have occurred along with improvements in walking and fatigue outcomes [49,[58][59][60].…”

Section: Exercise Training and Its Influence On Physical Fitness In Msmentioning

confidence: 99%

The Importance of Physical Fitness in Multiple Sclerosis

Motl¹

2013

J Nov Physiother

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Multiple Sclerosis (MS) is a common and life-altering neurological disease among adults in the United States and worldwide. This disease has an estimated prevalence of 1 per 1,000 adults in the United States [1] with the majority of cases occurring in women of European descent. The MS pathophysiology initially involves episodic periods of immune-mediated demyelination and transection of axons within the Central Nervous System (CNS). This results in the disruption of saltatory conduction of action potentials along myelinated axonal pathways in the brain, spinal cord, and optic nerves. The MS pathophysiology later transitions into a neurodegenerative disease process, presumably associated with insufficient neurotrophic support, and results in the accumulation of irreversible neurologic disability. The degree and location of axonal and neuronal damage within the CNS result in the heterogeneous expression of symptomatic, functional, and participatory consequences among persons with MS [2]. Such manifestations might be initiated or worsened by physical inactivity and resulting physiological deconditioning.We have previously described a model of physical inactivity, deconditioning, and worsening MS [3,4], and this was based on a similar framework for persons with chronic disease conditions [5] including MS [6]. The model is displayed in figure 1 and indicates that MS onset results in physical inactivity [7,8] that initiates physiological deconditioning (i.e., compromised or reduced physical fitness). This physiological deconditioning, in turn, results in worsening of MS, as indicated by loss of brain structure and function as well as symptomatic (e.g., fatigue) and functional (e.g., walking impairment) manifestations. The worsening of MS results in further physical inactivity and subsequent physiological deconditioning thereby yields a cycle of associations among physical inactivity, deconditioning, and worsening MS that develops over time. This model is important as it conceptualizes the importance of maintaining and improving physical fitness levels in persons with MS. Physical fitness might provide a form of "physiological reserve" that is protective of disease consequences and worsening of MS and this is consistent with other literatures such as cancer [9].To that end, this paper provides a comprehensive review of research on physical fitness in persons with MS. We begin by defining physical fitness and its domains as well as differentiating it from physical activity. We then present research on physiological deconditioning (i.e., detraining that manifests as a reduction in domains of physical work capacity or fitness) in persons with MS as well as evidence on the association between markers of physical fitness and consequences of MS. We lastly review research regarding the effects of exercise training on physical fitness and consequences of MS, and conclude with recently developed exercise recommendations for improving physical fitness. Our goal is the provision of a paper that underscores the (a) importance of p...

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Resistance training improves muscle strength and functional capacity in multiple sclerosis

Abstract: The present study provides level III evidence supporting the hypothesis that lower extremity progressive resistance training can improve muscle strength and functional capacity in patients with multiple sclerosis.

Cited by 226 publications

References 22 publications

Physical activity and exercise priorities in community dwelling people with multiple sclerosis: a Delphi study

Physical activity and exercise priorities in community dwelling people with multiple sclerosis: a Delphi study

Therapeutic Yoga: Symptom Management for Multiple Sclerosis

The Importance of Physical Fitness in Multiple Sclerosis

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