Resistance to the organophosphate temephos: Mechanisms, evolution and reversion in an Aedes aegypti laboratory strain from Brazil

Melo-Santos, Maria Alice Varjal de; Varjal-Melo, J.J.M.; Araújo, Ana Paula de; Gomes, Tatiane Cibele Souza; Paiva, Marcelo Henrique Santos; Regis, Lêda; Furtado, André Freire; Magalhães, Tereza; Macoris, M. L. G.; Andrighetti, Maria Teresa Macoris; Ayres, Constância Flávia Junqueira

doi:10.1016/j.actatropica.2009.10.015

Cited by 140 publications

(108 citation statements)

References 34 publications

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“…Previous studies showed that temephos resistance is widespread in the Caribbean and South America, and this resistance is strongly associated with increased activity of glutathione S-transferases, α-esterases and β-esterases, and, to a lesser degree, mixed function oxidases. 9,47 Because diflubenzuron and pyriproxyfen have never been used in public health programs in Martinique, it is possible that the cross-tolerance of mosquito larvae to IGR has arisen through the extensive use of temephos for vector control. This suggestion may have operational consequences for dengue vector control and the future use of IGRs if these products may contribute to selection for existing resistance mechanisms in natural populations of Ae.…”

Section: Discussionmentioning

confidence: 99%

Field Efficacy of New Larvicide Products for Control of Multi-Resistant Aedes aegypti Populations in Martinique (French West Indies)

Marcombe¹,

Darriet²,

Agnew³

et al. 2011

The American Journal of Tropical Medicine and Hygiene

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Abstract. World-wide dengue vector control is hampered by the spread of insecticide resistance in Aedes aegypti . We report the resistance status of a wild Ae. aegypti population from Martinique (Vauclin) to conventional larvicides ( Bacillus thuringiensis var israeliensis [ Bti ] and temephos) and potential alternatives (spinosad, diflubenzuron, and pyriproxyfen). The efficacy and residual activity of these insecticides were evaluated under simulated and field conditions. The Vauclin strain exhibited a high level of resistance to temephos, a tolerance to insect growth regulators, and full susceptibility to spinosad and Bti . In simulated trials, pyriproxyfen and Bti showed long residual activities in permanent breeding containers (28 and 37 weeks), whereas under field conditions they failed to curtail Ae. aegypti populations after four weeks. Conversely, diflubenzuron and spinosad showed a residual efficacy of 16 weeks, suggesting that these chemicals may be promising alternatives to Bti and temephos for controlling insecticide-resistant Ae. aegypti populations.

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Section: Discussionmentioning

confidence: 99%

Field Efficacy of New Larvicide Products for Control of Multi-Resistant Aedes aegypti Populations in Martinique (French West Indies)

Marcombe¹,

Darriet²,

Agnew³

et al. 2011

The American Journal of Tropical Medicine and Hygiene

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“…aegypti y el insecticida temefós, Melo-Santos, et al, (40) obtuvieron en Brasil una reversión de la resistencia a este organofosforado en experimentos llevados a cabo en el laboratorio con una cepa de campo resistente para evaluar tres escenarios diferentes en cuanto a la intensidad de la presión con temefós y al ingreso de individuos sensibles, y en todos ellos encontraron reversión de la resistencia, lo que demuestra que es posible recuperar la sensibilidad al temefós. En una población de Brasil (Juazeiro do Norte) se observó una disminución de los grados de resistencia, que pasaron de 10,2 a 7,2 después de la suspensión del uso de este organofosforado y su sustitución por Bacillus thuringiensis israelensis (41).…”

Section: Pruebas Biológicas De La Oms Con El Insecticida Temefós En Lunclassified

Evaluación de la susceptibilidad a insecticidas en poblaciones de Aedes aegypti (Diptera: Culicidae) del departamento de Caldas, Colombia, en los años 2007 y 2011

Conde

Orjuela

Castellanos³

et al. 2014

biomedica

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“…The genetic structure of A. albopictus populations have implications for vector control program, since, studies on selection pressure in A. aegypti populations using insecticides such as organophosphates and/ or pyrethroids under laboratory conditions, show the fixation of the population resistance phenotype in only a few generations [81][82][83][84][85] .…”

Section: Discussionmentioning

confidence: 99%

How much is known about the genetic diversity of the Asian tiger mosquito? A systematic review

Aguirre-Obando

Navarro-Silva

2017

revsal

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Introduction: Aedes (Stegomyia) albopictus (Skuse, 1894) is a vector for dengue and chikungunya viruses in the field, along with around 24 additional arboviruses under laboratory conditions. Knowledge of the genetic diversity of insect vectors is critical for the effective control and elimination of vector-borne diseases. Objective: We determined the current scenario of the genetic diversity in natural populations of A. albopictus through a systematic review. Methodology: It was possible to establish the first reports and distribution of A. albopictus populations in the world, as well as its genetic diversity, population genetic structure and molecular markers used to determine its genetic diversity. Results: A. albopictus is distributed worldwide with genetically structured populations and low diversity; however, 89.5% of the genetic diversity known is based on the use of RFLP, allozymes, isozymes, and mtDNA molecular markers that exhibit significant problems according to the literature. After the results were obtained, a critical analysis was carried out and existing shortcomings were detected. Conclusion: The current knowledge of genetic diversity of A. albopictus is based on genetic markers that exhibit significant problems reported in the literature; therefore, vector control programs targeting A. albopictus populations, may be compromised.

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Resistance to the organophosphate temephos: Mechanisms, evolution and reversion in an Aedes aegypti laboratory strain from Brazil

Cited by 140 publications

References 34 publications

Field Efficacy of New Larvicide Products for Control of Multi-Resistant Aedes aegypti Populations in Martinique (French West Indies)

Field Efficacy of New Larvicide Products for Control of Multi-Resistant Aedes aegypti Populations in Martinique (French West Indies)

Evaluación de la susceptibilidad a insecticidas en poblaciones de Aedes aegypti (Diptera: Culicidae) del departamento de Caldas, Colombia, en los años 2007 y 2011

How much is known about the genetic diversity of the Asian tiger mosquito? A systematic review

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