Resistance to HIV-1 Infection

Broad Human Immunodeficiency Virus (HIV)–Specific T Cell Responses to Conserved HIV Proteins in HIV‐Seronegative Women Highly Exposed to a Single HIV‐Infected Partner

“…HEPS women lacked the CCR5-D32 allele, resembled other northern Thai HLA-typed populations in allele frequencies [53], and did not differ from RW, all HIV-seropositive subjects, or CW, at the HLA-A and B loci. Thus we did not confirm previous associations of HEPS status with HLA-A*11, A*26, B*18, B*38, B*52, and B*77 [11,[54][55][56]. The finding of a reduced frequency of HLA-Cw*07 in HW, compared with HIV-seropositive per-sons, has not previously been reported and would easily become insignificant if adjusted for the multiple comparisons required for HLA alleles.…”

Modulating influence on HIV/AIDS by interactingRANTESgene variants

“…Seroconversion date was estimated as the midpoint between the last seronegative and the first seropositive HIV-1 antibody test date (mean interval 0.79 years, range 0.07 to 3.0 years). High-risk exposed uninfected subjects (n ϭ 271) were those with high-risk exposure through sharing of injection equipment (32), anal receptive sex with multiple partners (33), or transfusions with factor VIII clotting factor before 1984 when heat treatment was initiated (34). AF088219).…”

The multicenter AIDS Cohort Study, 1983 to …

“…Detels et al, J Acquir Immune Defic Syndr 1994;7:1263–9 3 Study: resistant vs susceptible men who have sex with menInterpretation: CD8 cells may modulate outcome of HIV exposure …”