2010
DOI: 10.1016/j.coph.2010.06.006
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Resistance or decreased susceptibility to glycopeptides, daptomycin, and linezolid in methicillin-resistant Staphylococcus aureus

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Cited by 152 publications
(90 citation statements)
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“…3 MRSA is resistant to all known β-lactam antibiotics, and reduced susceptibility to last-line antibiotics such as vancomycin, linezolid and daptomycin has also been reported. 4 …”
Section: Introductionmentioning
confidence: 99%
“…3 MRSA is resistant to all known β-lactam antibiotics, and reduced susceptibility to last-line antibiotics such as vancomycin, linezolid and daptomycin has also been reported. 4 …”
Section: Introductionmentioning
confidence: 99%
“…Nonsusceptibility to daptomycin has also been associated with changes in the structure and function of the cell envelope and surface charge. Linezolid resistance is associated with mutations in the 23S rRNA, although acquired resistance has now been documented (Nannini et al, 2010).…”
Section: Discussionmentioning
confidence: 99%
“…Many of the reported cases of infections caused by linezolid-resistant MRSA have been associated with deep organ, foreign body, nosocomial outbreaks, and/or prolonged therapy with Linezolid (usually more than three weeks) [14,46].…”
Section: Linezolid On Treatment Of Multiresistant Bacteriamentioning
confidence: 99%
“…Mutations associated with ribosomal proteins also affect the activity of linezolid. It has recently been discovered that an RNA methyltransferase, called Cfr, is the cause of a new phenotype of resistance to phenicols and clindamycin, which also confers resistance to oxazolidinones) [14,46].…”
Section: Linezolid On Treatment Of Multiresistant Bacteriamentioning
confidence: 99%
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