“…However, faulty attachment of HSV to transformed cells continues to remain suspect, since viral transformation of cells often results in profound alterations in the plasma membrane (17) which could conceivably affect viral attachment and penetration. However, if such changes occurred in HDC-17SA7 cells, it did not appear to affect virus adsorption since both HSV types attached rapidly to the plasma membrane, consistent with studies of HSV replication in cells transformed by other viruses (3, 6,7,18).…”