Resistance of drosophila to cadmium: Biochemical factors in resistant and sensitive strains

Genetic Basis of a between-Environment Trade-off Involving Resistance to Cadmium in Drosophila melanogaster

“…Unpolluted test is known from earlier work that the resistance provided in Drosophila by metallothionein regulatory gene(s) have these characteristics. That the genes that regulate the expression of metallothionein are on the X-chromosome was shown by Gill et al (1989) and sex-linkage of resistance to cadmium by Christie et al (1985). It is possible, therefore, that the gene for resistance identified here is a metallothionein regulatory gene.…”

“…Looking at the results of the crosses and backcrosses (Figs. 3, 5, 6), they fall into the pattern that one would expect from simple Mendelian genetics if it is assumed that: (1) the lines used to set up the initial crosses were homozygous; (2) resistance is controlled by a single locus with two alleles, resistant and susceptible, the resistant allele being dominant; and (3) the locus is located on or controlled from the Xchromosome (Gill et al 1989). Note that male Drosophila have only a single X-chromosome.…”

Genetic Basis of a between-Environment Trade-off Involving Resistance to Cadmium in Drosophila melanogaster

“…Unpolluted test is known from earlier work that the resistance provided in Drosophila by metallothionein regulatory gene(s) have these characteristics. That the genes that regulate the expression of metallothionein are on the X-chromosome was shown by Gill et al (1989) and sex-linkage of resistance to cadmium by Christie et al (1985). It is possible, therefore, that the gene for resistance identified here is a metallothionein regulatory gene.…”

“…Looking at the results of the crosses and backcrosses (Figs. 3, 5, 6), they fall into the pattern that one would expect from simple Mendelian genetics if it is assumed that: (1) the lines used to set up the initial crosses were homozygous; (2) resistance is controlled by a single locus with two alleles, resistant and susceptible, the resistant allele being dominant; and (3) the locus is located on or controlled from the Xchromosome (Gill et al 1989). Note that male Drosophila have only a single X-chromosome.…”

Adaptive Role of Inversion Polymorphism of Drosophila subobscura in Lead Stressed Environment

“…It was shown that increased tolerance to cadmium in D . melanogaster was linked to the presence of sex chromosome that originated from partially cadmium-resistant line of the species [ 39 ], as well as that one or more genes responsible for metallothionein structural gene expression regulation were located on sex chromosome [ 40 ]. The A 1 inversion in the DS population showed a significant change in frequency after three generations of exposure to lead.…”

Metapopulation Dynamics of Fruit Flies Undergoing Evolutionary Change in Patchy Environments

“…1, revealed that they were due to a single dominant sex-linked allele present in the original stock at low frequency (Shirley and Sibly 1999). It is known from earlier work that the resistance provided in Drosophila by metallothionein regulatory gene(s) has these characteristics (Christie et al 1985, Gill et al 1989). Since in Exp.…”

Genetic Basis of a between-Environment Trade-off Involving Resistance to Cadmium in Drosophila melanogaster

“…Unpolluted test is known from earlier work that the resistance provided in Drosophila by metallothionein regulatory gene(s) have these characteristics. That the genes that regulate the expression of metallothionein are on the X-chromosome was shown by Gill et al (1989) and sex-linkage of resistance to cadmium by Christie et al (1985). It is possible, therefore, that the gene for resistance identified here is a metallothionein regulatory gene.…”

“…Looking at the results of the crosses and backcrosses (Figs. 3, 5, 6), they fall into the pattern that one would expect from simple Mendelian genetics if it is assumed that: (1) the lines used to set up the initial crosses were homozygous; (2) resistance is controlled by a single locus with two alleles, resistant and susceptible, the resistant allele being dominant; and (3) the locus is located on or controlled from the Xchromosome (Gill et al 1989). Note that male Drosophila have only a single X-chromosome.…”

Adaptive Role of Inversion Polymorphism of Drosophila subobscura in Lead Stressed Environment

“…It was shown that increased tolerance to cadmium in D . melanogaster was linked to the presence of sex chromosome that originated from partially cadmium-resistant line of the species [ 39 ], as well as that one or more genes responsible for metallothionein structural gene expression regulation were located on sex chromosome [ 40 ]. The A 1 inversion in the DS population showed a significant change in frequency after three generations of exposure to lead.…”

Metapopulation Dynamics of Fruit Flies Undergoing Evolutionary Change in Patchy Environments

“…1, revealed that they were due to a single dominant sex-linked allele present in the original stock at low frequency (Shirley and Sibly 1999). It is known from earlier work that the resistance provided in Drosophila by metallothionein regulatory gene(s) has these characteristics (Christie et al 1985, Gill et al 1989). Since in Exp.…”

Genetic Basis of a between-Environment Trade-off Involving Resistance to Cadmium in Drosophila melanogaster

“…Unpolluted test is known from earlier work that the resistance provided in Drosophila by metallothionein regulatory gene(s) have these characteristics. That the genes that regulate the expression of metallothionein are on the X-chromosome was shown by Gill et al (1989) and sex-linkage of resistance to cadmium by Christie et al (1985). It is possible, therefore, that the gene for resistance identified here is a metallothionein regulatory gene.…”

“…Looking at the results of the crosses and backcrosses (Figs. 3, 5, 6), they fall into the pattern that one would expect from simple Mendelian genetics if it is assumed that: (1) the lines used to set up the initial crosses were homozygous; (2) resistance is controlled by a single locus with two alleles, resistant and susceptible, the resistant allele being dominant; and (3) the locus is located on or controlled from the Xchromosome (Gill et al 1989). Note that male Drosophila have only a single X-chromosome.…”

Adaptive Role of Inversion Polymorphism of Drosophila subobscura in Lead Stressed Environment

“…It was shown that increased tolerance to cadmium in D . melanogaster was linked to the presence of sex chromosome that originated from partially cadmium-resistant line of the species [ 39 ], as well as that one or more genes responsible for metallothionein structural gene expression regulation were located on sex chromosome [ 40 ]. The A 1 inversion in the DS population showed a significant change in frequency after three generations of exposure to lead.…”

Metapopulation Dynamics of Fruit Flies Undergoing Evolutionary Change in Patchy Environments

“…1, revealed that they were due to a single dominant sex-linked allele present in the original stock at low frequency (Shirley and Sibly 1999). It is known from earlier work that the resistance provided in Drosophila by metallothionein regulatory gene(s) has these characteristics (Christie et al 1985, Gill et al 1989). Since in Exp.…”