Resistance Exercise Performed at Different Degrees of Arterial Occlusion Pressure does not Induce Prolonged Oxidative Stress or Muscle Damage

Freitas, Eduardo

doi:10.23937/2469-5718/1510075

Cited by 3 publications

(14 citation statements)

References 30 publications

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“…However, even without prescribing exercises until failure, Neto et al [40] and Centner et al [18] presented a higher training volume for the HLRE group of ~28% and 7%, respectively when compared to LLRE-BFR. Only two studies [41,43] attempted to equalize training volume between LLRE-BFR and LLRE during fixed repetition schemes, while for LLRE-BFR vs HLRE, two studies equalized the training volume [46,47]. All trials in this systematic review did not report any adverse events.…”

Section: Exercise Protocolmentioning

confidence: 98%

“…The 13 studies in this review are summarized in Table 1 and included 158 subjects. Eight studies used a cross-over/inter-subject design [18,[36][37][38][39][40][41][42] and five studies used a parallel design PLOS ONE [43][44][45][46][47]. Included studies generally consisted of small sample sizes ranging from six [43] to twenty-eight subjects [47].…”

Section: Study Selection and Sample Characteristicsmentioning

confidence: 99%

“…The studied populations were young male subjects between 18 and 35 years old. Five studies were composed of resistance trained subjects [18,36,37,40,41], four trials were conducted in physically / recreationally active men [38,39,44,47], one study classified its subjects as athletes [42], but provided no details about their training routine, while another three studies included sedentary/untrained subjects [43,45,46].…”

Section: Study Selection and Sample Characteristicsmentioning

confidence: 99%

“…Four of the thirteen studies performed both upper and lower limb resistance exercise [36,38,39,47] whereas five studies performed just upper [38,39,42,44,45], and four performed just lower limb exercises [18,41,44,45]. LLRE intensity varied between 20-50% 1RM while exercise in the HLRE varied between 70-80% 1RM.…”

Section: Exercise Protocolmentioning

confidence: 99%

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Acute effect of low-load resistance exercise with blood flow restriction on oxidative stress biomarkers: A systematic review and meta-analysis

et al. 2023

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Background The purpose of this review was to analyze the acute effects of low-load resistance exercise with blood flow restriction (LLE-BFR) on oxidative stress markers in healthy individuals in comparison with LLE or high-load resistance exercise (HLRE) without BFR. Materials and methods A systematic review was performed in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. These searches were performed in CENTRAL, SPORTDiscus, EMBASE, PubMed, CINAHL and Virtual Health Library- VHL, which includes Lilacs, Medline and SciELO. The risk of bias and quality of evidence were assessed through the PEDro scale and GRADE system, respectively. Results Thirteen randomized clinical trials were included in this review (total n = 158 subjects). Results showed lower post-exercise damage to lipids (SMD = -0.95 CI 95%: -1.49 to -0. 40, I2 = 0%, p = 0.0007), proteins (SMD = -1.39 CI 95%: -2.11 to -0.68, I2 = 51%, p = 0.0001) and redox imbalance (SMD = -0.96 CI 95%: -1.65 to -0.28, I2 = 0%, p = 0.006) in favor of LLRE-BFR compared to HLRE. HLRE presents higher post-exercise superoxide dismutase activity but in the other biomarkers and time points, no significant differences between conditions were observed. For LLRE-BFR and LLRE, we found no difference between the comparisons performed at any time point. Conclusions Based on the available evidence from randomized trials, providing very low or low certainty of evidence, this review demonstrates that LLRE-BFR promotes less oxidative stress when compared to HLRE but no difference in levels of oxidative damage biomarkers and endogenous antioxidants between LLRE. Trial registration Register number: PROSPERO number: CRD42020183204.

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Section: Exercise Protocolmentioning

confidence: 98%

Section: Study Selection and Sample Characteristicsmentioning

confidence: 99%

Section: Study Selection and Sample Characteristicsmentioning

confidence: 99%

Section: Exercise Protocolmentioning

confidence: 99%

See 2 more Smart Citations

Acute effect of low-load resistance exercise with blood flow restriction on oxidative stress biomarkers: A systematic review and meta-analysis

et al. 2023

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“…As mentioned above, the original protocols designed for the KAATSU-Master and BFR resistance exercise used loads of 20 to 30% 1RM with 4 sets of exercises composed of 1 set of 30 repetitions followed by 3 sets of 15 repetitions with 1-min rest periods between sets and at a cadence of 1.5s in both the eccentric and concentric portions of the movement ( Freitas et al, 2017 ; Miller et al, 2018 ). When multiple exercises are used (usually 2 or 3 total exercises for a given session, like 2 leg press, followed knee extension, and knee flexion), then rest periods between exercises are usually between 3 and 5min.…”

Section: Anaerobic Exercises With Blood Flow Restrictionmentioning

confidence: 99%

The Evolution of Blood Flow Restricted Exercise

2021

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The use of blood flow restricted (BFR) exercise has become an accepted alternative approach to improve skeletal muscle mass and function and improve cardiovascular function in individuals that are not able to or do not wish to use traditional exercise protocols that rely on heavy loads and high training volumes. BFR exercise involves the reduction of blood flow to working skeletal muscle by applying a flexible cuff to the most proximal portions of a person’s arms or legs that results in decreased arterial flow to the exercising muscle and occluded venous return back to the central circulation. Safety concerns, especially related to the cardiovascular system, have not been consistently reported with a few exceptions; however, most researchers agree that BFR exercise can be a relatively safe technique for most people that are free from serious cardiovascular disease, as well as those with coronary artery disease, and also for people suffering from chronic conditions, such as multiple sclerosis, Parkinson’s, and osteoarthritis. Potential mechanisms to explain the benefits of BFR exercise are still mostly speculative and may require more invasive studies or the use of animal models to fully explore mechanisms of adaptation. The setting of absolute resistive pressures has evolved, from being based on an individual’s systolic blood pressure to a relative measure that is based on various percentages of the pressures needed to totally occlude blood flow in the exercising limb. However, since several other issues remain unresolved, such as the actual external loads used in combination with BFR, the type of cuff used to induce the blood flow restriction, and whether the restriction is continuous or intermittent, this paper will attempt to address these additional concerns.

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Effect of Blood Flow Restriction Technique on Delayed Onset Muscle Soreness: A Systematic Review

et al. 2022

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Background and Objectives: The effect of the blood flow restriction technique (BFR) on delayed onset muscular soreness (DOMS) symptoms remains unclear. Since there is no consensus in the literature, the aim of the present study is to systematically identify and appraise the available evidence on the effects of the BFR technique on DOMS, in healthy subjects. Materials and Methods: Computerized literature search in the databases Pubmed, Google Scholar, EBSCO, Cochrane and PEDro to identify randomized controlled trials that assessed the effects of blood flow restriction on delayed onset muscular soreness symptoms. Results: Eight trials met the eligibility criteria and were included in this review, presenting the results of 118 participants, with a mean methodological rating of 6/10 on the PEDro scale. Conclusions: So far, there is not enough evidence to confirm or refute the influence of BFR on DOMS, and more studies with a good methodological basis are needed, in larger samples, to establish protocols and parameters of exercise and intervention. Data analysis suggests a tendency toward the proinflammatory effect of BFR during high restrictive pressures combined with eccentric exercises, while postconditioning BFR seems to have a protective effect on DOMS. Prospero ID record: 345457, title registration: “Effect of Blood Flow Restriction Technique on the Prevention of Delayed Onset Muscle Soreness: A Systematic Review”.

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Resistance Exercise Performed at Different Degrees of Arterial Occlusion Pressure does not Induce Prolonged Oxidative Stress or Muscle Damage

Cited by 3 publications

References 30 publications

Acute effect of low-load resistance exercise with blood flow restriction on oxidative stress biomarkers: A systematic review and meta-analysis

Acute effect of low-load resistance exercise with blood flow restriction on oxidative stress biomarkers: A systematic review and meta-analysis

The Evolution of Blood Flow Restricted Exercise

Effect of Blood Flow Restriction Technique on Delayed Onset Muscle Soreness: A Systematic Review

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