Resistance Exercise Attenuates High-Fructose, High-Fat-Induced Postprandial Lipemia

Abstract

INTRODUCTIONMeals rich in both fructose and fat are commonly consumed by many Americans, especially young men, which can produce a significant postprandial lipemic response. Increasing evidence suggests that aerobic exercise can attenuate the postprandial increase in plasma triacylglycerols (TAGs) in response to a high-fat or a high-fructose meal. However, it is unknown if resistance exercise can dampen the postprandial lipemic response to a meal rich in both fructose and fat.METHODSEight apparently healthy men (Mean ± SEM; age = 27 ± 2 years) participated in a crossover study to examine the effects of acute resistance exercise on next-day postprandial lipemia resulting from a high-fructose, high-fat meal. Participants completed three separate two-day conditions in a random order: (1) EX-COMP: a full-body weightlifting workout with the provision of additional kilocalories to compensate for the estimated net energy cost of exercise on day 1, followed by the consumption of a high-fructose, high-fat liquid test meal the next morning (day 2) (~600 kcal) and the determination of the plasma glucose, lactate, insulin, and TAG responses during a six-hour postprandial period; (2) EX-DEF: same condition as EX-COMP but without exercise energy compensation on day 1; and (3) CON: no exercise control.RESULTSThe six-hour postprandial plasma insulin and lactate responses did not differ between conditions. However, the postprandial plasma TAG concentrations were 16.5% and 24.4% lower for EX-COMP (551.0 ± 80.5 mg/dL × 360 minutes) and EX-DEF (499.4 ± 73.5 mg/dL × 360 minutes), respectively, compared to CON (660.2 ± 95.0 mg/dL × 360 minutes) (P < 0.05).CONCLUSIONSA single resistance exercise bout, performed ~15 hours prior to a high-fructose, high-fat meal, attenuated the postprandial TAG response, as compared to a no-exercise control condition, in healthy, resistance-trained men.

Fructose Consumption in the Development of Obesity and the Effects of Different Protocols of Physical Exercise on the Hepatic Metabolism

“…As previously discussed, there are fewer publications about strength exercise than aerobic exercise. The only study that investigated the acute effects of strength exercise with high fructose diet in humans was carried out by Wilburn and colleagues [ 120 ]. On the first day of intervention, participants performed 14 different strength exercises (4 sets of 10 repetitions each with 90 s rest between sets) during 95 min.…”

Fructose co‐ingestion to increase carbohydrate availability in athletes

“…; Wilburn et al . ). In addition, elite athletes typically display exquisite metabolic health, as demonstrated by a 3‐fold higher insulin sensitivity than controls (Manetta et al .…”

“…Therefore, more research in the area of fructose-rich diets and their potential adverse effects are warranted. However, exercise appears to be able to correct early markers of metabolic disease induced by high fructose intake, independent of energy balance (Egli et al 2013;Wilburn et al 2015). In addition, elite athletes typically display exquisite metabolic health, as demonstrated by a 3-fold higher insulin sensitivity than controls (Manetta et al 2000) despite consuming large amounts (>450 g per day) of simple sugars during events such as the Tour de France (Saris et al 1989).…”

Exercise to Lower Postprandial Lipemia: Why, When, What and How

“…TAG reduction of 22% (range 4 to 35%) [14,28,[37][38][39][40][41][42][43][44][45][46]29,[47][48][49][50][51][52][53][54][55][56]30,[57][58][59][60][61][62][63][64][65][66]31,67,68,[32][33][34][35][36]. iv.…”