Abstract:Action potential conduction in axons triggers trans‐membrane ion movements, where Na
+
enters and K
+
leaves axons, leading to disruptions in resting trans‐membrane ion gradients that must be restored for optimal axon conduction, an energy dependent process. The higher the stimulus frequency, the greater the ion movements and the resulting energy demand. In the mouse optic nerve (MON), the stimulus evoked compound action potential (CAP) displays a triple peaked pro… Show more
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