Residue dissipation and dietary exposure risk assessment of methoxyfenozide in cauliflower and tea via modified <scp>QuEChERS</scp> using <scp>UPLC/MS/MS</scp>

Sun, Hong; Zhou, Li; Zhang, Xinzhong; Luo, Fengjian; Yang, Mei; Wang, Xinru; Lou, Zhengyun; Chen, Zongmao

doi:10.1002/jsfa.10179

Cited by 14 publications

(16 citation statements)

References 22 publications

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“…The half-lives in the other three provinces (Beijing, Anhui, and Shandong) were quite close, which were 3.0, 4.0, 5.1 days for methoxyfenozide, and were 1.3, 2.5, and 2.3 days for metaflumizone. The results were close to the dissipation rates of methoxyfenozide in cauliflower [16], of which the half-lives were 2.5-3.5 days.…”

Section: Dissipation Of Methoxyfenozide and Metaflumizone In Chinese Broccoli Under Field Conditionssupporting

confidence: 78%

“…A few reports have been published about residue analysis of methoxyfenozide and metaflumizone in vegetables. Sun et al [16] studied the residue dissipation of methoxyfenozide in cauliflower and tea by a modified QuEChERS sample preparation method combined with UHPLC-MS/MS, and they found that methoxyfenozide dissipated rapidly in cauliflower with a half-life of 2.5-3.5 days. Dong et al [17] developed a method for determination of metaflumizone residues in cabbage and soil by UHPLC-MS/MS using primary secondary amine (PSA) sorbent for cleanup.…”

Section: Introductionmentioning

confidence: 99%

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Method validation and residue analysis of methoxyfenozide and metaflumizone in Chinese broccoli under field conditions by liquid chromatography with tandem mass spectrometry

Yao

Han

et al. 2021

J of Separation Science

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Methoxyfenozide and metaflumizone are insecticides used on Chinese broccoli to prevent insects and increase yield. However, the residues are potentially harmful to the environment and consumers. In this study, the quick, easy, cheap, effective, rugged, safe method with high-performance liquid chromatography with tandem mass spectrometry was modified and validated for determination of methoxyfenozide and metaflumizone in Chinese broccoli. The clean-up efficiency of different sorbents including C 18 , primary secondary amine, graphitized carbon black, and carbon nanofiber was compared. Recoveries of the validated method were 71.8-94.6% with relative standard deviations of 1.5-3.2% and the limits of quantification were 0.01 and 0.005 mg/kg for methoxyfenozide and metaflumizone, respectively. A storage stability test showed almost no degradation of methoxyfenozide in Chinese broccoli, however, the degradation rate of metaflumizone was 22.9% after 10-wk storage at -20 • C. In field trials in four producing regions, the dissipation of both methoxyfenozide and metaflumizone in Chinese broccoli was fast, with half-lives of only 1.0-5.1 and 0.7-2.5 days, respectively. Terminal residues after application of the two pesticides were all below 1.0 mg/kg after 5 days.

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Section: Dissipation Of Methoxyfenozide and Metaflumizone In Chinese Broccoli Under Field Conditionssupporting

confidence: 78%

Section: Introductionmentioning

confidence: 99%

Method validation and residue analysis of methoxyfenozide and metaflumizone in Chinese broccoli under field conditions by liquid chromatography with tandem mass spectrometry

Yao

Han

et al. 2021

J of Separation Science

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“…For the safe application of propiconazole, dietary exposure calculation and risk assessment were studied based on the risk quotient (RQ) method. RQ < 100% indicates that the human exposure concentration by consumption of pesticide‐containing food is lower than the predicted effect concentration, representing an acceptable risk to humans, whereas RQ > 100% indicates unacceptable adverse health effects on humans 19–21 …”

Section: Methodsmentioning

confidence: 99%

Study on degradation behaviour, residue distribution, and dietary risk assessment of propiconazole in celery and onion under field application

Bai

Chen

et al. 2020

J Sci Food Agric

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BACKGROUND Propiconazole is widely used to control fungal diseases in field crops, including celery and onion. The potential risk to the environment and human health has aroused much public concern. Therefore, it is significant to investigate the degradation behaviour, residue distribution, and dietary risk assessment of propiconazole in celery and onion. RESULTS A sensitive analytical method for determination of propiconazole residue in celery and onion was established and validated through high‐performance liquid chromatography tandem mass spectrometry. The average recovery rate of propiconazole ranged from 85.7% to 101.8%, with a relative standard deviation of 2.1–6.3%. For the dissipation kinetics, the data showed that propiconazole in celery and onion was degraded, with half‐lives of 6.1–6.2 days and 8.7–8.8 days respectively. In the terminal residue experiments, the residues of propiconazole were below 4.66 mg kg−1 in celery after application two or three times and were below 0.029 mg kg−1 in onion after application of three or four times with an interval of 14 days under the designed dosages. The chronic and acute dietary exposure assessments for propiconazole were valued by risk quotient, with all values being lower than 100%. CONCLUSION Propiconazole in celery and onion was rapidly degraded following first‐order kinetics models. The dietary risk of propiconazole through celery or onion was negligible to consumers. The study not only offers a valuable reference for reasonable usage of propiconazole on celery and onion, but also facilitates the establishment of maximum residue limits in China. © 2020 Society of Chemical Industry

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“…19 To the best of our knowledge, scarcely any studies about the simultaneous determination of tolfenpyrad, dinotefuran and its metabolites in tea have been reported to date. Furthermore, although research has been carried out on the dissipation of pesticides during tea planting, processing and brewing, 1,3,4,[20][21][22][23][24] scarcely any literature has reported in the residue behavior and brewing transfer of tolfenpyrad, dinotefuran and its metabolites in tea. Therefore, it is significant to establish a reliable method for the simultaneous determination of tolfenpyrad, dinotefuran and its metabolites in tea, and use this to investigate their behavior during tea growth and tea brewing.…”

Section: Introductionmentioning

confidence: 99%

Residue behavior, transfer and risk assessment of tolfenpyrad, dinotefuran and its metabolites during tea growing and tea brewing

Bai

Chen

et al. 2021

J Sci Food Agric

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BACKGROUND: Tolfenpyrad and dinotefuran are two representative pesticides used for pest control in tea gardens. Their application may bring about a potential risk to the health of consumers. Therefore, it is essential to investigate the residue behavior, transfer and risk assessment of tolfenpyrad, dinotefuran and metabolites from tea garden to teacup.RESULTS: An effective analytical method was established and validated to simultaneously determine tolfenpyrad, dinotefuran and its metabolites (DN and UF) in tea. The average recoveries of tolfenpyrad, dinotefuran, DN and UF were in the range 72.1-106.3%, with relative standard deviations lower than 11.8%. On the basis of the proposed method, the dissipation of tolfenpyrad and dinotefuran in fresh tea leaves followed first-order kinetics models with half-lives of 4.30-7.33 days and 4.65-5.50 days, respectively. With application amounts of 112.5-168.75 g a.i. ha -1 once or twice, the terminal residues of tolfenpyrad and total dinotefuran in green tea were lower than 19.6 and 7.13 mg kg −1 , respectively, and below their corresponding maximum residue limits . The leaching rates of tolfenpyrad and total dinotefuran during the tea brewing were in the ranges 1.4-2.3% and 93.7-98.1%, respectively. CONCLUSION: Tolfenpyrad and dinotefuran in tea were easily degraded. The RQ c and RQ a values for tolfenpyrad were 37.6% and 5.4%, which were much higher than for dinotefuran at 24.7% and 0.84%, respectively. The data indicated that there was no significant health risk in tea for consumers at the recommended dosages. The results provide scientific data regarding the reasonable use of tolfenpyrad and dinotefuran aiming to ensure safe tea consuption.

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Residue dissipation and dietary exposure risk assessment of methoxyfenozide in cauliflower and tea via modified QuEChERS using UPLC/MS/MS

Cited by 14 publications

References 22 publications

Method validation and residue analysis of methoxyfenozide and metaflumizone in Chinese broccoli under field conditions by liquid chromatography with tandem mass spectrometry

Method validation and residue analysis of methoxyfenozide and metaflumizone in Chinese broccoli under field conditions by liquid chromatography with tandem mass spectrometry

Study on degradation behaviour, residue distribution, and dietary risk assessment of propiconazole in celery and onion under field application

Residue behavior, transfer and risk assessment of tolfenpyrad, dinotefuran and its metabolites during tea growing and tea brewing

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