Residual serum fibrinogen as a universal biomarker for all serotypes of Myasthenia gravis
Faraz S. Hussain,
Ramanaguru S. Piragasam,
Hassan Sarker
et al.
Abstract:Myasthenia Gravis (MG) is an autoimmune disease associated with severe neuromuscular weakness. Diagnostic confirmation of MG is typically delayed and secured in about 85% and 50% of patients with generalized and ocular MG, respectively with serum antibodies. We have identified a sensitive and specific diagnostic biomarker for various MG serotypes with quantitative proteomics. Serum proteomes of 18 individuals (MG patients, healthy controls (HC), Rheumatoid Arthritis (RA) were quantified in a pilot study and oc… Show more
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