Residual dynamic and risk assessment of dimethomorph in Swiss chard grown at two different sites

Abstract

Residue analysis of dimethomorph in Swiss chard cultivated at two different locations under greenhouse conditions was conducted using high-performance liquid chromatography-ultraviolet detection and confirmed by tandem mass spectrometry. The randomly collected samples (over 14 days) were extracted with acetonitrile and purified using a Florisil solid-phase extraction cartridge. Linearity over a concentration range of 0.05-50.0 mg/L had an excellent coefficient of determination of 0.9996. Recovery rate ranged from 82.98 to 95.43% with relative standard deviations ≤5.12% and limits of detection and quantification of 0.003 and 0.01 mg/kg, respectively. The initial deposits [day 0 (2 h post-application)] were considerably lower (7.57 and 8.55 mg/kg for sites 1 and 2, respectively) than the maximum residue limit (30 mg/kg) set by the Korean Ministry of Food and Drug Safety. The dissipation half-life was approximately the same, being 5.0 and 5.1 days for sites 1 and 2, respectively. Risk assessment estimated as acceptable daily intake revealed a value of 0.084 or 0.094% (day 0) and 0.014% (10 days post-application), for sites 1 and 2, respectively. The values indicated that dimethomorph can be safely used on Swiss chard, with no hazardous effects expected for Korean consumers.

Dissipation behavior of chlorpyrifos residues and risk assessment in sugarcane fields

“…In addition, such variations are expected because of variations in the pesticide type. For example, the rates of decline of dimethomorph in Swiss chard grown at two different sites had a similar pattern (Kabir et al, ).…”

Comparative Transcriptome Analysis to Investigate the Immunotoxicity Mechanism Triggered by Dimethomorph on Human Jurkat T Cell Lines

“…Since the use of DMM is very extensive, some reports in recent years have shown that the content of water, soil, and agricultural products of DMM range from ng/kg to mg/kg [ 18 ] and pose a certain risk to living organisms, including aquatic organisms, birds, and mammals [ 19 , 20 ]. Therefore, numerous studies have been performed to determine the dissipation and residue of DMM in vegetables, fruits, and their processed products [ 19 , 20 , 21 , 22 ]. More importantly, many studies have demonstrated that DMM is toxic to some soil and water microflora, birds, and mammals, even at very low concentrations [ 18 , 20 ].…”

Dissipation and Risk Assessment of Multiresidual Fungicides in Grapes under Field Conditions

“…Several different strategies have been employed to date as a means of measuring pyraclostrobin, dimethomorph, cymoxanil, cyazofamid, and CCIM residues in particular matrices. For example, gas chromatography (GC), high performance liquid chromatography with an ultraviolet visible detector (HPLC-UV), and mass spectrometry (MS) have all been employed to measure pyraclostrobin residues in grapes and other key crops. ,− Studies using a combination of GC and MS (GC-MS), HPLC-UV, and liquid chromatography with tandem mass spectrometry (LC-MS/MS) have been conducted for measuring dimethomorph in crops including grapes. − Cymoxanil has been detected via GC, GC-MS, HPLC-UV, and LC-MS/MS in assorted food matrixes. − Both LC and LC-MS/MS have been used for cyazofamid/CCIM residue measurements in grapes and other crops. , − At present, however, there are few reports regarding efforts to simultaneously detect all five of these compounds in grape field tests. As such, there is clear value in conducting such tests to better understand the multiresidue behavior of these compounds and to conduct appropriate risk assessments.…”