Residential Proximity to Large Numbers of Swine in Feeding Operations Is Associated with Increased Risk of Methicillin-Resistant Staphylococcus aureus Colonization at Time of Hospital Admission in Rural Iowa Veterans

Abstract

Among 1,036 patients, residential proximity within 1 mile of large swine facilities was associated with nearly double the risk of methicillin-resistant Staphylococcus aureus (MRSA) colonization at admission (relative risk, 1.8786 [95% confidence interval, 1.0928-3.2289]; P = .0239) and, after controlling for multiple admissions and age, was associated with nearly triple the odds of MRSA colonization (odds ratio, 2.76 [95% confidence interval, 1.2728-5.9875]; P = .0101).

Meticillin-resistant Staphylococcus aureus CC398 is an increasing cause of disease in people with no livestock contact in Denmark, 1999 to 2011

“…Likewise, land application of pig manure as fertiliser, by spray or injection, may also mediate environmental transmission. Two studies from the United States showed significant associations between the cropland application of pig manure and MRSA carriage [20,21]. However, in contrast to our study, these two American studies did not distinguish between people with and without livestock contact and did not report MRSA strain types.…”

“…aureus normally spreads through human-to-human contact [17] and this mode of transmission is likely to play a major role in the dissemination of MRSA CC398-IIa. Various studies suggest that environmental contamination of air and soil surfaces may also contribute to MRSA CC398 transmission [18–21]. Moreover, MRSA CC398 is a relatively common contaminant of retail meat in Europe [22], and food-borne transmission has been hypothesised as a possible source of infections in people with no livestock contact.…”

Reply to “The Natural Environment May Be the Most Important Source of Antibiotic Resistance Genes”

“…In another study, methicillin-resistant Staphylococcus aureus (MRSA) was tracked in 1,036 patients at the time that they were admitted to an Iowa hospital. Patients who lived within 1 mile of a large swine facility were almost three times more likely to carry MRSA than the general U.S. population (3). In another, quite elegant study, complete genome sequencing was used to follow a clade of Staphylococcus aureus strains in 19 countries on four continents.…”

Photodynamic Effect of Red Laser Radiation on the Growth of Staphylococcus aureus Strains with the Use of Photoditazine

“…Ключевые слова: золотистый стафилококк, лазерное излу-чение, фотодитазин. DOI: 10.18500/1816DOI: 10.18500/ -9775-2017 Золотистый стафилококк является возбу-дителем многих заболеваний человека и до последнего времени остается наиболее частой причиной возникновения внутрибольничных ин-фекций [1,2]. Особому риску подвергаются паци-енты с ослабленной иммунной системой при не-соблюдении персоналом больницы надлежащих санитарных правил.…”