A reactor model for the single-phase rotor-stator spinning disc reactor based on residence time distribution measurements is described. For the experimental validation of the model, the axial clearance between the rotor and both stators is varied from 1.0 3 10 23 to 3.0 3 10 23 m, the rotational disc speed is varied from 50 to 2000 RPM, and the volumetric flow rate is varied from 7.5 3 10 26 to 22.5 3 10 26 m 3 s 21 . Tracer injection experiments show that the residence time distribution can be described by a plug flow model in combination with 2-3 ideally stirred tanks-in-series. The resulting reactor model is explained with the effect of turbulence, the formation of Von K arm an and B€ odewadt boundary layers, and the effect of the volumetric flow rate.