Resection of Intrathoracic Paraganglioma With and Without Cardiopulmonary Bypass

Abstract

In this series, 73% of intrathoracic PGLs were functional and involved noradrenergic, mixed noradrenergic and dopaminergic, or pure dopaminergic secretion. Cardiac and pericardial paraganglioma resection may require cardiopulmonary bypass. Although intraoperative bleeding in most complex cases may be uncontrollable, as for 1 of our patients, those who survived hospital discharge had favorable long-term outcomes.

Outcomes of surgery for functional cardiac paragangliomas: A single-center experience of 17 patients

“…Therefore, we continued the preoperative medical treatment for our patients, the same as the newest report from the Mayo Clinic. 1 However, the specific regimen should be negotiated with endocrinologists.…”

“…Latest research stated that a 3-dimensional printing model would be helpful for familiarization with the anatomic interrelationship of tumor positioning within vascular structures. 1 We noticed that most functional cardiac paragangliomas could be completely resected in their primary surgery. Redo surgery for tumor recurrence remains challenging, and we have only one experience with a patient with a history of previous incomplete resection of atrial septal tumor (patient 11).…”

Management of Multiple Secreting Paragangliomas in a Succinate Dehydrogenase Subunit D (SDHD) Variant Carrier

“…Therefore, surgical excision is the treatment of choice in functional sPGLs. [3][4][5][6] The risks and benefits of PGL surgery warrant a careful multidisciplinary approach, as illustrated by this case presentation. A 29-year-old man reported a cervical mass and recurrent episodes of severe headache, palpitations, and hyperhidrosis.…”

Commentary: Management of cardiac paraganglioma is a team sport

“…Similar confines have been present in other recently published focused institutional experiences. 3,4 A perceived weakness of these studies is an apparent lack of address on what to do about bleeding. [2][3][4] Safe and successful embolization has been reported.…”

“…3,4 A perceived weakness of these studies is an apparent lack of address on what to do about bleeding. [2][3][4] Safe and successful embolization has been reported. 5 Why not do preoperative embolization?…”