Resection of an ameloblastoma in a pediatric patient and immediate reconstruction using a combination of tissue engineering and costochondral rib graft

Johnson, Jeanette; Jundt, Jonathon S.; Hanna, Issa; Shum, Jonathan; Badger, Gary R.; Melville, James C.

doi:10.1016/j.adaj.2016.06.010

Cited by 6 publications

(3 citation statements)

References 17 publications

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“…J. Johnson et al [ 21 ] and her colleagues combined costochondral rib graft, allogeneic bone, BMAC, and recombinant human morphogenetic protein-2 in an 11-year-old patient with a 3.4 × 4.2 × 3.1 cm defect. A 100% success has been reported in a 1-year study.…”

Section: Resultsmentioning

confidence: 99%

“…Literature on the use of rhBMP-2 in large maxillofacial defects in children is scarce. Only three papers included children (9–18 years) in their studies [ 17 , 18 , 21 ]. Although the predictability and safety of the combination of allogenic bone, BMAC, and BMP for reconstruction after resection of benign tumors in adult patients have been demonstrated, their use in children is still in dispute.…”

Section: Discussionmentioning

confidence: 99%

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Reconstruction of Critical Sized Maxillofacial Defects Using Composite Allogeneic Tissue Engineering: Systematic Review of Current Literature

Ramezanzade

Aeinehvand²,

Ziaei³

et al. 2023

Biomimetics

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The current review aimed to assess the reliability and efficacy of tissue-engineered composite grafts in the reconstruction of large maxillofacial defects resulting from trauma or a benign pathologic disease. A systematic review of the literature was conducted using PubMed/Medline, Embase, and Scopus up to March 2022. The eligibility criteria included patients who had been treated with composite allogeneic tissue engineering for immediate/delayed reconstruction of large maxillofacial defects with minimum/no bone harvesting site. In the initial search, 2614 papers were obtained, and finally, 13 papers were eligible to be included in the current study. Most included papers were case reports or case series. A total of 144 cases were enrolled in this systematic review. The mean age of the patients was 43.34 (age range: 9–89). Most studies reported a successful outcome. Bone tissue engineering for the reconstruction and regeneration of crucial-sized maxillofacial defects is an evolving science still in its infancy. In conclusion, this review paper and the current literature demonstrate the potential for using large-scale transplantable, vascularized, and customizable bone with the aim of reconstructing the large maxillofacial bony defects in short-term follow-ups.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Reconstruction of Critical Sized Maxillofacial Defects Using Composite Allogeneic Tissue Engineering: Systematic Review of Current Literature

Ramezanzade

Aeinehvand²,

Ziaei³

et al. 2023

Biomimetics

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“…The use of MMF was only mentioned in a few reports with a higher proportion of use in patients treated with "BMP with autografts" and "scaffolds with autografts" compared with other treatment groups. 20,21,29,32,37,39,[51][52][53]…”

Section: General Treatment Informationmentioning

confidence: 99%

Segmental Mandibular Reconstruction Using Tissue Engineering Strategies: A Systematic Review of Individual Patient Data

Kumar

Rometsch²,

Thor

et al. 2020

Craniomaxillofacial Trauma & Reconstruction

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Objective: The aim of the systematic review was to analyze the current clinical evidence concerning the use of tissue engineering as a treatment strategy for reconstruction of segmental defects of the mandible and their clinical outcomes using individual patient data. Methods: A systematic review of the literature was conducted using PubMed and Cochrane Library on May 21, 2019. The eligibility criteria included patients in whom segmental mandibular reconstruction was carried out using tissue engineering as the primary treatment strategy. After screening and checking for eligibility, individual patient data were extracted to the extent it was available. Data extraction included the type of tissue engineering strategy, demographics, and indication for treatment, and outcomes included clinical and radiographic outcome measures, vitality of engineered bone, dental rehabilitation, and patient-reported outcome measures and complications. Results: Out of a total of 408 articles identified, 44 articles reporting on 285 patients were included, of which 179 patients fulfilled the inclusion criteria. The different tissue engineering treatment strategies could be broadly classified into 5 groups: “prefabrication,” “cell culture,” “bone morphogenetic protein (BMP) without autografts,” “BMP with autografts,” and “scaffolds containing autografts.” Most included studies were case reports or case series. A wide variety of components were used as scaffolds, cells, and biological substances. There was not a single outcome measure that was both objective and consistently reported, although most studies reported successful outcome. Discussion: A wide variety of tissue engineering strategies were used for segmental mandibular reconstruction that could be classified into 5 groups. Due to the low number of treated patients, lack of standardized and consistent reporting outcomes, lack of comparative studies, and low evidence of reported literature, there is insufficient evidence to recommend any particular tissue engineering strategy.

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Current Methods of Maxillofacial Tissue Engineering

Melville

Mañón²,

Blackburn

et al. 2019

Oral and Maxillofacial Surgery Clinics of North America

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Resection of an ameloblastoma in a pediatric patient and immediate reconstruction using a combination of tissue engineering and costochondral rib graft

Cited by 6 publications

References 17 publications

Reconstruction of Critical Sized Maxillofacial Defects Using Composite Allogeneic Tissue Engineering: Systematic Review of Current Literature

Reconstruction of Critical Sized Maxillofacial Defects Using Composite Allogeneic Tissue Engineering: Systematic Review of Current Literature

Segmental Mandibular Reconstruction Using Tissue Engineering Strategies: A Systematic Review of Individual Patient Data

Current Methods of Maxillofacial Tissue Engineering

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