“…But, because cystadenoma and cystadenocarcinoma arising from simple liver cysts have been reported, long-term follow-up is needed, as was done for the present patient. 16,17 Surgical treatment, or the injection of chemical agents, such as absolute alcohol, 18 minocycline chloride, 19,20 and acetic acid, 21 should be undertaken in patients with persistent symptoms and evidence of cyst …”