Researches on sulphanilamide, para‐amino‐benzoic acid and their derivates V: On the mechanism of the action of sulphonamides and of <i>p</i>‐amino‐benzoic acid, with remarks on the action of ergons and anti‐ergons in general

Havinga, E.; Veldstra, H.

doi:10.1002/recl.19470660503

Recl. Trav. Chim. Pays‐Bas

1947

DOI: 10.1002/recl.19470660503

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Researches on sulphanilamide, para‐amino‐benzoic acid and their derivates V: On the mechanism of the action of sulphonamides and of p‐amino‐benzoic acid, with remarks on the action of ergons and anti‐ergons in general

E. Havinga

H. Veldstra

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1947

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Cited by 2 publications

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Researches on sulphanilamide, para‐amino‐benzoic acid and their derivatives. IV: The behaviour of sulphanilamide, p‐aminobenzoic acid and of their derivatives with respect to the mercury/solution interface (polarographic investigations) and to lecithin and protein monolayers

Veldstra

Havinga

1947

Recl. Trav. Chim. Pays‐Bas

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Sulphanilamide, p‐aminobenzoic acid and a number of their derivatives are studied polarographically in order to ascertain whether or not it is probable that p‐aminobenzoic acid functions in a redox system, and to compare their affinities for the rather apolar mercury/solution boundary. The latter serves to a certain extent as a model for a lipophilic membrane of a type within which London‐van der Waals' forces predominantly determine the degree of interaction. In this way very typical differences come to the fore which generally parallel those obtained in the investigations of U.V. absorption spectra and electrochemical properties, as well as the activity of the compounds in vivo. For p‐aminobenzoic acid it may be concluded that a direct function in a redox system is very improbable. In addition mono‐layers of lipoid or protein character are used as models for membranes in which other types of forces than those considered above play a rōle.

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Researches on sulphanilamide, para‐amino‐benzoic acid and their derivatives. IV: The behaviour of sulphanilamide, p‐aminobenzoic acid and of their derivatives with respect to the mercury/solution interface (polarographic investigations) and to lecithin and protein monolayers

Veldstra

Havinga

1947

Recl. Trav. Chim. Pays‐Bas

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Considerations on the interaction of ergons and their “substrates”

Veldstra

1947

Biochimica et Biophysica Acta

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Researches on sulphanilamide, para‐amino‐benzoic acid and their derivates V: On the mechanism of the action of sulphonamides and of p‐amino‐benzoic acid, with remarks on the action of ergons and anti‐ergons in general

Cited by 2 publications

References 36 publications

Researches on sulphanilamide, para‐amino‐benzoic acid and their derivatives. IV: The behaviour of sulphanilamide, p‐aminobenzoic acid and of their derivatives with respect to the mercury/solution interface (polarographic investigations) and to lecithin and protein monolayers

Researches on sulphanilamide, para‐amino‐benzoic acid and their derivatives. IV: The behaviour of sulphanilamide, p‐aminobenzoic acid and of their derivatives with respect to the mercury/solution interface (polarographic investigations) and to lecithin and protein monolayers

Considerations on the interaction of ergons and their “substrates”

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