Research progress on the lipid-lowering and weight loss effects of tea and the mechanism of its functional components

Zhang, Ziying; Liu, Changwei; Fang, Wen-Wen; Tang, Quanquan; Li, Zhan; Shi, Yu; Tang, Mengge; Z, Liu; Zhang, Sheng; Liu, Ailing

doi:10.1016/j.jnutbio.2022.109210

Cited by 5 publications

(1 citation statement)

References 107 publications

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“…Polyphenols are present in numerous foods and herbs, serving functions as antioxidants, blood vessel wall strengtheners, promoters of gastrointestinal digestion, reducers of blood fat, and inhibitors of bacteria. − Many foods, such as red wine and tea, encompass a variety of polyphenols, with tea being notably rich in these compounds, typically constituting 25 to 35% of the dry weight and directly impacting the flavor of the tea. Based on the production methods and the extent of fermentation, tea can be categorized into various types, which, in turn, determine the taste, efficacy, quality, and pricing of the tea.…”

Section: Introductionmentioning

confidence: 99%

Multilocus Distance-Regulated Sensor Array for Recognition of Polyphenols via Machine Learning and Indicator Displacement Assay

Ni,

Yu,

Gao

et al. 2023

Anal. Chem.

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Developing new strategies to construct sensor arrays that can effectively distinguish multiple natural components with similar structures in mixtures is an exceptionally challenging task. Here, we propose a new multilocus distance-modulated indicator displacement assay (IDA) strategy for constructing a sensor array, incorporating machine learning optimization to identify polyphenols. An 8-element array, comprising two fluorophores and their six dynamic covalent complexes (C1−C6) formed by pairing two fluorophores with three distinct distance-regulated quenchers, has been constructed. Polyphenols with diverse spatial arrangements and combinatorial forms compete with the fluorophores by forming pseudocycles with quenchers within the complexes, leading to varying degrees of fluorescence recovery. The array accurately and effectively distinguished four tea polyphenols and 16 tea varieties, thereby demonstrating the broad applicability of the multilocus distance-modulated IDA array in detecting polyhydroxy foods and natural medicines.

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Section: Introductionmentioning

confidence: 99%

Multilocus Distance-Regulated Sensor Array for Recognition of Polyphenols via Machine Learning and Indicator Displacement Assay

Ni,

Yu,

Gao

et al. 2023

Anal. Chem.

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Lovastatin Production by Wild Eurotium cristatum Isolated from Fuzhuan Brick Tea Produced Using Forest Resources in Auhua

Zheng

et al. 2023

Forests

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Fuzhuan brick tea is a dark tea produced using tea plant leaves, and its quality is strongly affected by Eurotium cristatum. The superior Eurotium cristatum strain could enhance functional components in Fuzhuan brick tea, improving its quality and economic value. To research the lipid-lowering substance of Eurotium cristatum in Fuzhuan brick tea from Anhua country tea production area, several wild-type Eurotium cristatum strains were screened for lovastatin production. Of all 20 wild-type strains, 6 Eurotium cristatum strains could produce lovastatin, and the H20 test strain could produce the highest lovastatin. The organ of lovastatin production was studied, and its yield in sexual propagule (ascospore and ascocarp) was the highest. Some fermentation parameters for lovastatin produced by the H20 strain were researched, and the optimum condition, such as PDA medium containing additional 8% soluble starch, 32 °C, and 120 r/min, are reported. These results are promising for developing one Fuzhuan brick tea with a high lipid-lowering function and expanding the scope of tea plant forest resource application.

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High-Value Utilization of Tea Forest Resources: Breeding Eurotium cristatum Strains to Enhance Lovastatin Yields in Anhua Dark Tea

Li,

Liu,

Liu

et al. 2023

Forests

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The tea plant is a vital strategic forest resource in China. Dark tea produced from its leaves is an indispensable health-promoting product in western China due to its unique lipid-lowering function. Eurotium cristatum is the dominant strain in Fuzhuan brick tea (a variety of Anhua dark tea) and could produce many functional components, including lovastatin, a lipid-lowering compound. In this study, the lovastatin yield of dark tea was improved by breeding Eurotium cristatum using the protoplast fusion method. The experiments were carried out by inducing a fusion between inactivated Eurotium cristatum JH1205 and Monascus CICC5031. Among the 92 fusants screened the HPLC method, four strains (A4, A36, A54, and A76) with higher lovastatin production (more than three times as high) were obtained. The A76 strain had the highest lovastatin yield, which was 23.93 μg/mL. The location of the tea forest strongly influenced the lovastatin yield of loose dark tea. The strain bred in this study improved the lovastatin yield of loose dark tea by more than three times when compared to wild Eurotium cristatum. These results are promising for the development of tea forest resources.

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Research progress on the lipid-lowering and weight loss effects of tea and the mechanism of its functional components

Cited by 5 publications

References 107 publications

Multilocus Distance-Regulated Sensor Array for Recognition of Polyphenols via Machine Learning and Indicator Displacement Assay

Multilocus Distance-Regulated Sensor Array for Recognition of Polyphenols via Machine Learning and Indicator Displacement Assay

Lovastatin Production by Wild Eurotium cristatum Isolated from Fuzhuan Brick Tea Produced Using Forest Resources in Auhua

High-Value Utilization of Tea Forest Resources: Breeding Eurotium cristatum Strains to Enhance Lovastatin Yields in Anhua Dark Tea

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