Research progress on the application of inkjet printing technology combined with hydrogels

Wu, Yuyao; Zhang, Yanzhen; Yan, Mingyu; Hu, Guofang; Li, Zihao; He, Weiwei; Wang, Xiaolong; Abulimit, Aibaibu; Li, Runsheng

doi:10.1016/j.apmt.2023.102036

Cited by 9 publications

(3 citation statements)

References 100 publications

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“…Inkjet printing is considered appropriate for multi-material processing since it can work with many printheads, offers high resolution, operates without physical contact, and has easily scalable processing capabilities [ 30 ]. Inkjet printing utilizes low-viscosity fluids and operates by shooting liquid ink droplets out of a nozzle and onto the target object [ 31 , 32 ] by a driving force ( Figure 1 a).…”

Section: The 3d Printing Of Hydrogelsmentioning

confidence: 99%

Three-Dimensional Printing of Hydrogels for Flexible Sensors: A Review

Khan,

Ahmad,

Zhu

et al. 2024

Gels

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The remarkable flexibility and heightened sensitivity of flexible sensors have drawn significant attention, setting them apart from traditional sensor technology. Within this domain, hydrogels—3D crosslinked networks of hydrophilic polymers—emerge as a leading material for the new generation of flexible sensors, thanks to their unique material properties. These include structural versatility, which imparts traits like adhesiveness and self-healing capabilities. Traditional templating-based methods fall short of tailor-made applications in crafting flexible sensors. In contrast, 3D printing technology stands out with its superior fabrication precision, cost-effectiveness, and satisfactory production efficiency, making it a more suitable approach than templating-based strategies. This review spotlights the latest hydrogel-based flexible sensors developed through 3D printing. It begins by categorizing hydrogels and outlining various 3D-printing techniques. It then focuses on a range of flexible sensors—including those for strain, pressure, pH, temperature, and biosensors—detailing their fabrication methods and applications. Furthermore, it explores the sensing mechanisms and concludes with an analysis of existing challenges and prospects for future research breakthroughs in this field.

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Section: The 3d Printing Of Hydrogelsmentioning

confidence: 99%

Three-Dimensional Printing of Hydrogels for Flexible Sensors: A Review

Khan,

Ahmad,

Zhu

et al. 2024

Gels

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“…Overall, inkjet printing of particulate-laden hydrogels holds significant promise in advancing biomedical applications [ 116 ]. Its ability to fabricate complex, multi-cellular structures with high precision makes it a valuable tool in tissue engineering, disease modeling, and drug delivery.…”

Section: Challenges and Opportunitiesmentioning

confidence: 99%

Engineering biomaterials by inkjet printing of hydrogels with functional particulates

Cheng,

Williamson,

Chiu

et al. 2024

Med-X

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Hydrogels with particulates, including proteins, drugs, nanoparticles, and cells, enable the development of new and innovative biomaterials. Precise control of the spatial distribution of these particulates is crucial to produce advanced biomaterials. Thus, there is a high demand for manufacturing methods for particle-laden hydrogels. In this context, 3D printing of hydrogels is emerging as a promising method to create numerous innovative biomaterials. Among the 3D printing methods, inkjet printing, so-called drop-on-demand (DOD) printing, stands out for its ability to construct biomaterials with superior spatial resolutions. However, its printing processes are still designed by trial and error due to a limited understanding of the ink behavior during the printing processes. This review discusses the current understanding of transport processes and hydrogel behaviors during inkjet printing for particulate-laden hydrogels. Specifically, we review the transport processes of water and particulates within hydrogel during ink formulation, jetting, and curing. Additionally, we examine current inkjet printing applications in fabricating engineered tissues, drug delivery devices, and advanced bioelectronics components. Finally, the challenges and opportunities for next-generation inkjet printing are also discussed. Graphical Abstract

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“…In addition, hydrogels possess an easily modifiable surface with abundant functional groups, which can be physically or chemically decorated to induce many attractive physicochemical properties, including flexibility, softness, biodegradability, and biocompatibility [ 35 , 36 ]. In most cases, hydrogels can be prepared via physical or chemical approaches [ 37 , 38 , 39 , 40 ]. The chemical preparation of hydrogels commonly involves the use of certain crosslinking agents to evoke a crosslinking reaction with polymers that have specific functional groups.…”

Section: Introductionmentioning

confidence: 99%

Recent Research Progress on Polyamidoamine-Engineered Hydrogels for Biomedical Applications

Liu,

Li,

Yang

et al. 2024

Biomolecules

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Hydrogels are three-dimensional crosslinked functional materials with water-absorbing and swelling properties. Many hydrogels can store a variety of small functional molecules to structurally and functionally mimic the natural extracellular matrix; hence, they have been extensively studied for biomedical applications. Polyamidoamine (PAMAM) dendrimers have an ethylenediamine core and a large number of peripheral amino groups, which can be used to engineer various polymer hydrogels. In this review, an update on the progress of using PAMAM dendrimers for multifunctional hydrogel design was given. The synthesis of these hydrogels, which includes click chemistry reactions, aza-Michael addition, Schiff base reactions, amidation reactions, enzymatic reactions, and radical polymerization, together with research progress in terms of their application in the fields of drug delivery, tissue engineering, drug-free tumor therapy, and other related fields, was discussed in detail. Furthermore, the biomedical applications of PAMAM-engineered nano-hydrogels, which combine the advantages of dendrimers, hydrogels, and nanoparticles, were also summarized. This review will help researchers to design and develop more functional hydrogel materials based on PAMAM dendrimers.

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Research progress on the application of inkjet printing technology combined with hydrogels

Cited by 9 publications

References 100 publications

Three-Dimensional Printing of Hydrogels for Flexible Sensors: A Review

Three-Dimensional Printing of Hydrogels for Flexible Sensors: A Review

Engineering biomaterials by inkjet printing of hydrogels with functional particulates

Recent Research Progress on Polyamidoamine-Engineered Hydrogels for Biomedical Applications

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