Research progress on sample pretreatment methods for migrating substances from food contact materials

Self Cite

A highly chemically stable primary amide-functionalized cyclotricatechylene covalent organic framework was synthesized by an irreversible reaction and a post-synthetic modification. It possessed a rod-like morphology and exhibited strong solvent stability owing to the polyether bonds. The material showed good adsorption performance for melamine and its derivatives and adsorption mechanism was investigated by molecular simulations. The adsorbent was coated on the nylon-66 membrane to prepare the enrichment membrane. Under optimized conditions, an in-syringe membrane-based extraction method, combined with ultra-high performance liquid chromatography-tandem mass spectrometry was developed for the analysis of melamine and six melamine derivatives in the migration solution. A good linearity was obtained with correlation coefficients ranging from 0.9924 to 0.9995. The limits of detection were 1-200 ng/L and the limits of quantification were 3-500 ng/L. This method was successfully applied to the migration solution of sushi bamboo rolling mats with spiked recoveries of 73.2%-115% and relative standard deviations of 0.9%-9.9%. This work shows a practical and perspective approach for the efficient enrichment of food contact material hazards.

Section: Introductionmentioning

confidence: 99%

Primary amide‐functionalized cyclotricatechylene covalent organic frameworks membrane for efficient enrichment of melamine and its derivatives in migration solution of food contact materials

Lin

Ouyang

et al. 2023

Self Cite

“…Huelsmann et al in their review presented selected applications, describing the use of molecularly imprinted polymers, metal and covalent organic frameworks, ionic liquids and magnetic ionic liquids, and deep eutectic solvents as novel materials in sample preparation [6]. Ouyang and Lu in their review summarized the development of sample pretreatment methods for the analysis of migrating substances from FCMs till 2020 [7].…”

Section: Introductionmentioning

confidence: 99%

Βisphenol A and its analogs migrated from contact materials into food and beverages: An updated review in sample preparation approaches

Priovolos

Samanidou

2023

Bisphenols are used as monomers in the production of plastic materials, and they are likely to be detected in food contact materials. Due to their migration from these plastic packaging materials into food and beverages, the organoleptic properties of the products are changing and plenty of harmful effects on human health are caused, especially if consumers are exposed to higher levels of bisphenols than those established by legislation. However, because of their trace‐level presence, their determination into food and beverage matrices is rather difficult. For this reason, sensitive, simple, rapid, and green methods are required to extract and preconcentrate the analytes of interest. Effective and representative tests are required as well, to evaluate the migration of bisphenols from plastic materials under realistic usage conditions. This review provides a detailed background of bisphenol A chemistry and legislation. Furthermore, it refers to bisphenol A migration test procedures and the recent advances of the last decade in the extraction of bisphenols from various matrices by using different sample preparation techniques prior to their chromatographic determination.

“…In fact, the identification of unknown compounds in FCM, including NIAS, is an emerging analytical field [14][15][16]. For a wide-range compound detection, liquid chromatography (LC) coupled to high resolution accurate mass spectrometry (HRMS) is currently the most used technique, mainly with hybrid quadrupole-time-of-flight (Q-TOF) and Q-Orbitrap detectors [15], providing information on accurate mass and fragmentation pattern.…”

Section: Introductionmentioning

confidence: 99%

Liquid chromatography‐Orbitrap Tribrid high‐resolution mass spectrometry using data dependent‐tandem mass spectrometry with triple stage fragmentation as a screening tool to perform identification and risk assessment of unknown substances in food contact epoxy resin

Miralles

López

Dualde

et al. 2021

A new, fast, and automatic approach has been applied for the tentative identification of unknown substances released by food contact epoxy resin after performing a migration test with food simulant. This approach combines intelligent data acquisition with AcquireX linked to liquid chromatography‐Orbitrap Tribrid high‐resolution mass spectrometry using data dependent‐tandem mass spectrometry with triple stage fragmentation coupled to Compound Discoverer™ software for automated data processing and compound identification. The identification of the observed features was performed using a set of identification criteria, including exact mass, isotope pattern, tandem mass spectrometry spectra match, and retention time. With these criteria, 263 substances were tentatively identified. Most of the identified compounds were additives, such as plasticisers, stabilizers, and antioxidants, used in different plastic applications. However, metabolites, biological constituents with pharmacological activity, and other substances with industrial applications were also detected. In order to perform a risk assessment of the food contact epoxy resin, threshold of toxicological concern approach was applied for the identified compounds. There was not risk associated with the migration of the identified substances.