Research progress of stimuli-responsive ZnO-based nanomaterials in biomedical applications

Abstract

Zinc oxide nanoparticles (ZnO NPs), an attractive oxide semiconductor material, are widely used in the biomedical fields due to their good biosafety and economy. The proposal of stimuli-responsive materials provides...

Progress of Piezoelectric Semiconductor Nanomaterials in Sonodynamic Cancer Therapy

“…With increasing attention to photodynamic therapy, the potential of ZnO for SDT has gradually developed. By the stimulation of external energy, such as light, ultrasound, and radiation, nanoparticles with piezoelectric properties convert energy into charge separation and generate electron/hole pairs to produce ROS by redox reactions with substances in the cellular environment …”

“…By the stimulation of external energy, such as light, ultrasound, and radiation, nanoparticles with piezoelectric properties convert energy into charge separation and generate electron/hole pairs to produce ROS by redox reactions with substances in the cellular environment. 54 Metal oxides are a class of catalysts of great interest, which can cause the detachment of oxygen in the lattice under specific external environments (such as high temperature, reduction treatment), leading to oxygen deficiency and the formation of oxygen vacancies. 55 Surface oxygen vacancies can effectively adjust the conduction band position, thereby reducing the band gap and making it easier for electron− hole pairs to separate.…”

ZnO based 0–3D diverse nano-architectures, films and coatings for biomedical applications

“…These ZNSs have been tailored [11][12][13] in view of their multifunctional applications including solar cells, light emitting diodes, field emission, gas sensors, biosensors, thin protecting films, drug delivery, photodegradation, etc. [14][15][16][17][18] Moreover, due to promising intrinsic properties, i.e., viability, bioacceptability, high isoelectric point, tunable morphology, etc., ZNSs are found suitable for various biomedical applications such as antimicrobial, biosensing, bioimaging, drug delivery, anticancer, diagnosis, wound healing, etc. 8,[19][20][21] More specifically, ZNSs have been extensively investigated in biomedical applications due to their biocompatibility and ease of tailoring their optical, electrical, structural, and morphological properties.…”

“…These ZNSs have been tailored 11–13 in view of their multifunctional applications including solar cells, light emitting diodes, field emission, gas sensors, biosensors, thin protecting films, drug delivery, photodegradation, etc . 14–18 Moreover, due to promising intrinsic properties, i.e. , viability, bio-acceptability, high isoelectric point, tunable morphology, etc.…”

Design of BODIPY functional ZIF-90 towards enhanced visible-light driven antibacterial performance

“…4,5 Compared with traditional antibacterial materials, nanomaterials have attracted much attention because of their multiple antibacterial effects and no bacteria resistance. [6][7][8][9][10][11] Many different families of nanomaterials (including noble-metal nanoparticles, [12][13][14] metal oxide, [15][16][17] metal sulfide, 18 carbon-based nanomaterials 9,19 and metalorganic frameworks (MOFs) 20,21 ) have been developed to control and combat bacterial infection. MOFs are a class of inorganic-organic hybrid porous polymers built from metal ions and organic ligands.…”