Research progress of sensors based on molecularly imprinted polymers in analytical and biomedical analysis

Ni, Xu; Tang, Xue; Wang, Dan; Zhang, Jingjing; Zhao, Linjie; Gao, Jie; He, Hua; Dramou, Pierre

doi:10.1016/j.jpba.2023.115659

Cited by 6 publications

(2 citation statements)

References 162 publications

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“…Enhancing mechanical [22,36,40,41,60,67,70,, electrical [21,27,[30][31][32]35,42,55,59,120,, and microstructural [19,53,63,68,118, attributes in nanocomposites requires precise nanoscale manipulation. This is coupled with issues like reproducibility, cost, and complexity in preparation, adding to the intricacies of nanomaterial research [231][232][233][234][235][236][237][238][239][240][241][242][243][244][245][246][247][248][249][250]. As nanotechnology evolves, addressing these technical and ethical issues is crucial for maximizing the potential of nanomaterials and ensuring their responsible application in various fields [277][278][279][280].…”

Section: Introductionmentioning

confidence: 99%

A 30-Year Review on Nanocomposites: Comprehensive Bibliometric Insights into Microstructural, Electrical, and Mechanical Properties Assisted by Artificial Intelligence

Gomes Souza,

Bhansali,

Pal

et al. 2024

Materials

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From 1990 to 2024, this study presents a groundbreaking bibliometric and sentiment analysis of nanocomposite literature, distinguishing itself from existing reviews through its unique computational methodology. Developed by our research group, this novel approach systematically investigates the evolution of nanocomposites, focusing on microstructural characterization, electrical properties, and mechanical behaviors. By deploying advanced Boolean search strategies within the Scopus database, we achieve a meticulous extraction and in-depth exploration of thematic content, a methodological advancement in the field. Our analysis uniquely identifies critical trends and insights concerning nanocomposite microstructure, electrical attributes, and mechanical performance. The paper goes beyond traditional textual analytics and bibliometric evaluation, offering new interpretations of data and highlighting significant collaborative efforts and influential studies within the nanocomposite domain. Our findings uncover the evolution of research language, thematic shifts, and global contributions, providing a distinct and comprehensive view of the dynamic evolution of nanocomposite research. A critical component of this study is the “State-of-the-Art and Gaps Extracted from Results and Discussions” section, which delves into the latest advancements in nanocomposite research. This section details various nanocomposite types and their properties and introduces novel interpretations of their applications, especially in nanocomposite films. By tracing historical progress and identifying emerging trends, this analysis emphasizes the significance of collaboration and influential studies in molding the field. Moreover, the “Literature Review Guided by Artificial Intelligence” section showcases an innovative AI-guided approach to nanocomposite research, a first in this domain. Focusing on articles from 2023, selected based on citation frequency, this method offers a new perspective on the interplay between nanocomposites and their electrical properties. It highlights the composition, structure, and functionality of various systems, integrating recent findings for a comprehensive overview of current knowledge. The sentiment analysis, with an average score of 0.638771, reflects a positive trend in academic discourse and an increasing recognition of the potential of nanocomposites. Our bibliometric analysis, another methodological novelty, maps the intellectual domain, emphasizing pivotal research themes and the influence of crosslinking time on nanocomposite attributes. While acknowledging its limitations, this study exemplifies the indispensable role of our innovative computational tools in synthesizing and understanding the extensive body of nanocomposite literature. This work not only elucidates prevailing trends but also contributes a unique perspective and novel insights, enhancing our understanding of the nanocomposite research field.

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Section: Introductionmentioning

confidence: 99%

A 30-Year Review on Nanocomposites: Comprehensive Bibliometric Insights into Microstructural, Electrical, and Mechanical Properties Assisted by Artificial Intelligence

Gomes Souza,

Bhansali,

Pal

et al. 2024

Materials

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“…A novel MIP-ECL sensor is constructed by combining sensitive and controllable ECL sensor with highly specific MIP technology, which has a wide application prospect in life science, food safety, and environmental monitoring Liu and Ko, 2023;Ni et al, 2023). MIP-ECL sensors can be further divided into Ru-bpy system and Luminol-H 2 O 2 system according to the different electrochemical luminescence signals.…”

Section: Introductionmentioning

confidence: 99%

Stable and reproducible MIP-ECL sensors for ultra-sensitive and accurate quantitative detection of Estrone

Cao,

Chen

2024

Front. Bioeng. Biotechnol.

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Estrone (E1), as an endogenous estrogen, has a variety of physiological functions in human body and is of great significance to human health. On the other hand, it is a widely distributed and highly disturbing environmental endocrine disruptor in water. Therefore, there is an urgent need to develop a sensitive, rapid, and inexpensive method for the on-site determination of E1, which is not only for clinical diagnosis and treatment, but also for the investigation and monitoring of endogenous estrogen pollution in environmental water. In this study, Ru(bpy)32+/MWCNTs/Nafion/gold electrodes were prepared by surface electrostatic adsorption and ion exchange. A molecularly imprinted membrane (MIP) with the capability to recognize E1 molecules was prepared by sol-gel method, and the electrodes were modified with MIP to form an electrochemical luminescence sensor (MIP-ECL). This method simultaneously possesses ECL’s advantage of high sensitivity and MIP’s advantage of high selectivity. Moreover, the addition of carboxylated multi-walled carbon nanotubes (MWCNT-COOH) improved the functionalization of the gold electrode surface and increased the binding sites of MIP. Meanwhile, the good conductivity of MWCNTs promoted electron transfer and further improved the sensitivity of the sensor. The sensor showed a wide linear interval in which the E1 concentrations can range from 0.1 μg/L to 200 μg/L, along with a high linear correlation coefficient (R2 = 0.999). The linear regression equation of the sensor was Y = 243.64x-79.989, and the detection limit (LOD) was 0.0047 μg/L. To validate our sensor, actual samples were also measured by the reference method (LC-MS/MS), and it was found that the relative deviation of quantitative results of the two different methods was less than 4.1%. This indicates that the quantitative results obtained by this sensor are accurate and can be used for rapid in situ determination of E1 in clinical samples and environmental water.

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Molecularly Imprinted Polymeric Biomaterials in Diagnosis and Medical Practice

Göktürk,

Güler,

Yılmaz

et al. 2024

Biomedical Materials & Devices

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Research progress of sensors based on molecularly imprinted polymers in analytical and biomedical analysis

Cited by 6 publications

References 162 publications

A 30-Year Review on Nanocomposites: Comprehensive Bibliometric Insights into Microstructural, Electrical, and Mechanical Properties Assisted by Artificial Intelligence

A 30-Year Review on Nanocomposites: Comprehensive Bibliometric Insights into Microstructural, Electrical, and Mechanical Properties Assisted by Artificial Intelligence

Stable and reproducible MIP-ECL sensors for ultra-sensitive and accurate quantitative detection of Estrone

Molecularly Imprinted Polymeric Biomaterials in Diagnosis and Medical Practice

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