Research progress of EMT in Cancer Metastasis

Abstract

Cancer is still a deadly disease that haunts people. Once there is a malignant tumor, patients need to receive a series of expensive, complex and painful treatments. Even so, cancer still causes high mortality, for its ability to easily metastasizing to other organs, without effective cures for any kind of cancer so far. Therefore, researchers have been trying to explore its mechanism and find ways to inhibit its development and discover new cure from various aspects. The latest research found that Epithelial-Mesenchymal Transitions (EMT) may be related to cancer, especially in the metastasis. It can be a breakthrough finding that render cancer a curable disease. In this paper, we systematically introduce the definition, classification, mechanism, influencing factors of EMT and its relationship with cancer metastasis and provide new angles and ideas for further exploring all levels of signal pathways and cancer treatment.