Research Progress in the Visual Sensors/Sensing Ensembles for L-Cysteine

Study of Rhodamine‐Based Fluorescent Probes for Organic Radical Intermediates

“…A series of rhodamine-based fluorescent probes was synthesized via the reaction of rhodamine B with substituted benzylamines (1)(2)(3)(4)(5), alkyl amines (6-10), or aryl amines (11-22, Scheme 2). These compounds were then used in the detection of organic radical intermediates (Scheme 3), produced from the thermal homolysis of traditional radical initiators such as di-tbutyl peroxide (DTBP), 2,2-azobisisobutyronitrile (AIBN), t-butyl peroxyacetate (TBPA), and t-butyl hydroperoxide (TBHP).…”

“…Fluorescent probes have been widely used and explored over the past several decades because they offer unique photophysical properties to sensitively monitor metal ions, anions, reactive oxygen species, biomolecules, and bioprocess. [1] Among the various fluorophore scaffolds, rhodamine derivatives are promising candidates for fluorescent probes due to their high quantum yield, high sensitivity, and excellent chemical and photo stability. Several excellent reviews highlighting rhodamine-based fluorescent probes for metal ions, reactive oxygen species, and pH have been reported.…”

Recent Progress in Fluorescent Probes for Diabetes Visualization and Drug Therapy

“…H 2 S not only adjusts the insulin sensitivity in insulin-targeted organs but also preserves intracellular redox homeostasis [101]. Cys serves as a vital scavenger of ROS under mitochondrial oxidative stress, which is very vital in the biosystem [102]. Therefore, it is of great significance to research the relations and connections between mitochondrial oxidative stress and diabetes by monitoring the levels or behaviors of Cys in mitochondria.…”