Research progress in the development of 3D skin models and their application to in vitro skin irritation testing
Hongxia Lu,
Xulei Zuo,
Jiayu Yuan
et al.
Abstract:Toxicological assessment of chemicals is crucial for safeguarding human health and the environment. However, traditional animal experiments are associated with ethical, technical, and predictive limitations in assessing the toxicity of chemicals to the skin. With the recent development of bioengineering and tissue engineering, three‐dimensional (3D) skin models have been commonly used as an alternative for toxicological studies. The skin consists of the subcutaneous, dermis, and epidermis. All these layers hav… Show more
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