Research progress in pharmacological activities and structure-activity relationships of tetralone scaffolds as pharmacophore and fluorescent skeleton

Synthesis of 8-Methoxy-1-Tetralone

“…We wish to mention here that recently tetralone scaffolds and their therapeutic applications have been reported (Gaumi et al, 2021;Sheng et al, 2022).…”

Insights into the Origin and Therapeutic Implications of Benzopyran and Its Derivatives

“…[82][83] Naturally occurring fused form of furanone and pyranonaphthoquinone are the basic frame to play a smart role in medicinal chemistry. Kalafungin (10) natural exiting compounds bearing the above-mentioned pharmacophore were tested for the treatment of leukemic cells and AKT kinase. [84][85] Naturally occurring pyranonapthoquinone's derivatives possessed biological activities were obtained from various living organisms such as including fungi, bacteria and higher plants.…”

“…Natural drugs are extracted from plants and animals while pharmaceutical companies synthesize artificial drugs. [8] According to the literature, our focus is on the therapeutic activity of benzopyran derivatives which shows broad biological activities, including anticancer, [9][10] antibacterial, [11] antidiabetic, and antiinflammatory, [12][13] antitumor, antimicrobial, [14] anticoagulant, [15] antioxidant, [16] anti-spasmolytic, antifungal, [17] antiviral, [16] anti-helminthic, antitubercular, [18] and anticonvulsant. [19] Moreover, in the reported literature, some more activities are available like diuretic, estrogenic, hypothermal, anti-HIV, [20] analgesic, and vasodilatory properties.…”

New Insights Into the Origin and Therapeutic Implications of Benzopyran and Their Derivatives: A Review

“…Natural drugs extract from plants and animals while artificial drugs synthesize by a pharmaceutical company [8]. According to the literature, our focused on the therapeutic activity of benzopyran derivatives which shows broad biological activities, including anticancer [9], [10], antibacterial [11], antidiabetic and anti-inflammatory [12], [13], antitumor, antimicrobial [14], anticoagulant [15], antioxidant [16], anti-spasmolytic, antifungal [17], antiviral [16], anti-helminthic, antitubercular [18], and anticonvulsant [19]. Moreover, in the reported literature, some more activities are available like a diuretic, estrogenic, hypothermal, anti-HIV [20], analgesic, and vasodilatory properties.…”