Research progress and future prospects of the mechanism of probiotics in the treatment of allergic rhinitis

Abstract

At present, allergic rhinitis has become a worldwide disease. And it has caused serious harm to people, so people urgently need an efficient and safe way such as using probiotics to treat it. The current mainstream view is that allergic rhinitis is mainly caused by Th1 / Th2 or Th17 / Treg cell imbalance. Probiotics can repair the intestinal barrier, regulate the balance of Th1 and Th2, prevent the excessive differentiation of Th2, correct the imbalance of Th17 and Treg, and produce some anti-inflammatory metabolites to treat allergic rhinitis. However, the therapeutic effect of probiotics is influenced by multiple factors. This paper mainly discusses the influence of the selection of probiotics, the intervention time and duration of probiotics, and the route of administration on the therapeutic effect. However, the therapeutic effect of probiotics is seriously impacted by multiple factors. This paper mainly discusses the influence of the selection of probiotics, the intervention time and duration of probiotics, and the route of administration on the therapeutic effect, in order to propose some fresh directions for the remedy of allergic rhinitis in the future.