The digital economy plays an important role in promoting regional green innovation. Based on the panel data of 30 provincial administrative regions in mainland China (except Tibet) from 2011 to 2018, this paper constructs a comprehensive development index of the digital economy and explores the potential path of the digital economy affecting regional green innovation through factor analysis and regression analysis. The results show the following: Firstly, the digital economy can effectively promote regional green innovation capability. The causal relationship is mainly realized through scientific research funds and human resources. Secondly, in terms of regional heterogeneity, the role of the digital economy in promoting green innovation and R&D investment in eastern China is stronger than that in central and western China. Thirdly, further analysis showed that the digital economy has a significant nonlinear influence on regional green innovation capability. This feature is mainly reflected in the influence of R&D personnel on regional green innovation. Therefore, the rational allocation of R&D resources is conducive to the development of regional green innovation. Finally, it is suggested to improve the two mechanisms of R&D funds and personnel investment to actuate regional green innovation development.