The paper discusses the issue of the influence of the growth of the operation parameters of power plant components on the fatigue phenomena that take place under mechanical and thermal loading. The loading characteristics have been taken as measurements results in industrial conditions. Stress-strain characteristics of such components, which take into consideration the changeable properties of materials subject to fatigue, have been described. The hardening processes of the materials, which are assumed to be used in designed power plants, have also been discussed. The aim of the paper is the description of the mechanical behaviour of the power plant components taking into consideration the real industrial conditions of their operation and changeable mechanical properties of the components’ materials.