Research on the clinical treatment of hypertriglyceridemia and acute pancreatitis

Abstract

Hypertriglyceridemia is the third most common cause of acute pancreatitis in the world [1]. In China, hypertriglyceridemia is gradually rising as the second leading cause of acute pancreatitis [2]. The disease usually occurs in patients with an underlying disorder of lipoprotein metabolisms and secondary conditions such as poorly controlled diabetes mellitus, alcohol abuse, or particular drug use. The clinical manifestations of pancreatitis caused by hypertriglyceridemia are generally similar to acute pancreatitis caused by other causes. However, patients with pancreatitis caused by hypertriglyceridemia may have a longer course of the disease and more complications [3], accompanied by a higher possibility of persistent organ failure. The initial treatment of pancreatitis due to hypertriglyceridemia is similar to that of acute pancreatitis from other causes. It includes aggressive fluid resuscitation, pain control, and nutritional support. In acute pancreatitis, timely recognition of hypertriglyceridemia is crucial in the initial and long-term management of the disease. It is also critical for preventing the recurrence of acute pancreatitis.