Realizing the sustainable innovation growth of enterprises is one of the important research directions of management science. Traditional enterprise growth innovation methods cannot effectively estimate the emotional tendency of online public opinion (PO), and they cannot guide the effective growth of enterprises. For this reason, This paper proposes an enterprise growth innovation technology based on the evolutionary game (EG) model of sustainable development and deep learning (DL). Firstly, by obtaining the game payment matrix between network users and enterprises, combined with the deep neural network model, the PO evolution model of the enterprise growth network was constructed and solved. Then, a convolutional neural network (CNN) model was used to extract sequence features from global information, and a gated recurrent unit (GRU) was used to consider the context. A DL network model based on CNN–GRU was proposed. Finally, by introducing the EG model, a stable strategy was generated through the dynamic adjustment of the whole system, which improved the accuracy of online PO judgment. Through simulation experiments, the enterprise growth innovation method proposed in this paper was compared with the other three methods. The results show that the accuracy, precision, recall, and f1 value of this method are 92.21%, 89.33%, 91.86%, and 91.64%, respectively, which are better than the other three methods. This method is of great significance for promoting enterprise innovation technology and sustainable development of enterprises.