This study aims to explore the application effect of precision anesthesia in elderly surgical patients. 82 elderly patients who underwent surgical treatment in our hospital from September 2021 to August 2023 were selected as the research subjects. The patients were divided into an observation group and a control group using a random table method, with 41 cases in each group. The control group used traditional anesthesia techniques for anesthesia management. The observation group used precision anesthesia technology to anesthetize patients. Compare the depth of anesthesia control, incidence of complications during anesthesia, and postoperative recovery between the two groups. The control group using precise anesthesia technology for anesthesia management was significantly better than the control group in terms of anesthesia control depth, incidence of complications during anesthesia, and postoperative recovery rate (p<0.05), promoting postoperative recovery and improving the prognosis of elderly patients during surgery. It has good safety and high clinical value, and is worth further research and promotion.