Research of Near-Infrared Small Living Animal Fluorescence Imaging System

Mao, 王懋 Wang; Chunyan, 李春炎 Li; Yunfei, 孙云飞 Sun; Min, 李敏 Li; Xiaomin, 翟晓敏 Zhai; Dongmin, 吴东岷 Wu

doi:10.3788/aos201333.0617003

Cited by 2 publications

(2 citation statements)

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“…[270,271] Gd-Ag 2 S and A1094@RGD-HBc are unique dual-modality nanoprobes that have been used to delineate brain tumors preoperatively. [272,273] Moreover, Gd-Ag 2 S integrates the advantages of deeper penetration depth with the strong MR imaging of Gd. [273] Another DSNPs@FSHP selectively exhibits efficient ovarian tumor-targeting properties.…”

Section:  Nir-ii Imaging Surgery Navigationmentioning

confidence: 99%

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Tracking tumor heterogeneity and progression with near‐infrared II fluorophores

Wang

et al. 2023

Exploration

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Heterogeneous cells are the main feature of tumors with unique genetic and phenotypic characteristics, which can stimulate differentially the progression, metastasis, and drug resistance. Importantly, heterogeneity is pervasive in human malignant tumors, and identification of the degree of tumor heterogeneity in individual tumors and progression is a critical task for tumor treatment. However, current medical tests cannot meet these needs; in particular, the need for noninvasive visualization of single‐cell heterogeneity. Near‐infrared II (NIR‐II, 1000–1700 nm) imaging exhibits an exciting prospect for non‐invasive monitoring due to the high temporal‐spatial resolution. More importantly, NIR‐II imaging displays more extended tissue penetration depths and reduced tissue backgrounds because of the significantly lower photon scattering and tissue autofluorescence than traditional the near‐infrared I (NIR‐I) imaging. In this review, we summarize systematically the advances made in NIR‐II in tumor imaging, especially in the detection of tumor heterogeneity and progression as well as in tumor treatment. As a non‐invasive visual inspection modality, NIR‐II imaging shows promising prospects for understanding the differences in tumor heterogeneity and progression and is envisioned to have the potential to be used clinically.

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Section:  Nir-ii Imaging Surgery Navigationmentioning

confidence: 99%

“…[272,273] Moreover, Gd-Ag 2 S integrates the advantages of deeper penetration depth with the strong MR imaging of Gd. [273] Another DSNPs@FSHP selectively exhibits efficient ovarian tumor-targeting properties. [274] The brightest organic dye, IR-FEP, can identify xenograft 4T1 tumors with 100% accuracy.…”

Section:  Nir-ii Imaging Surgery Navigationmentioning

confidence: 99%

Tracking tumor heterogeneity and progression with near‐infrared II fluorophores

Wang

et al. 2023

Exploration

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Study of near-infrared dispersion wave generation for microstructured fiber

Qijie¹,

Zhou²,

Shi³

et al. 2015

Acta Phys. Sin.

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Properties of nonlinear microstructured fiber fabricated in our laboratory are theoretically analyzed using the finite element method. This fiber has a high nonlinearity and phase matching for the dispersion wave generation. To achieve all-fiber nonlinearity in microstructured fiber, the dependence of dispersion wave on the pump power is investigated. When changing the pump power at 1032 nm with a femtosecond fiber laser, the near-infrared dispersion waves cover a region from 753 to 789 nm. The central wavelength and bandwidths alter obviously, and the fiber length has a remarkable impact on pulse broadening and frequency spectrum. Results coincide with the analyses. These results could be a reference for all-fiber nonlinearity of microstructured fiber, and lay a foundation for biological and medical applications, especially some researches on the near-infrared source for nonlinear light microscopy.

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Research of Near-Infrared Small Living Animal Fluorescence Imaging System

Cited by 2 publications

References 0 publications

Tracking tumor heterogeneity and progression with near‐infrared II fluorophores

Tracking tumor heterogeneity and progression with near‐infrared II fluorophores

Study of near-infrared dispersion wave generation for microstructured fiber

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