2020
DOI: 10.1044/2020_persp-20-00111
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Research in Speech Science and Voice Disorders: The Promise of Modern Genetic Approaches in Improving Clinical Diagnosis and Treatment

Abstract: Much of the research in speech science and voice biology characterizes disorders through observations of functional behaviors, physiological measurements (e.g., videostroboscopy, subglottic pressure, noninvasive electroencephalography, acoustics, etc.), and outcome metrics. This body of research contributes to our understanding of disease presentation and informs clinical assessment and treatment paradigms. However, when existing treatments are not consistently effective in empirical testing, these techniques … Show more

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“…The PRS for educational attainment significantly explained a small proportion of the variance of language and literacy at age 12, but its predictive ability was overall low and deemed not useful in the clinical setting [ 46 ]. In the neighboring field of speech and voice disorders, the use of genetic information in the clinical setting has also been advocated [ 47 ]. In addition to investigating the direct association between PRS for a relevant trait and developmental outcomes, clinical practice may also benefit, albeit not immediately, from studies into the genetic overlaps across language-related disorders and traits.…”
Section: Introductionmentioning
confidence: 99%
“…The PRS for educational attainment significantly explained a small proportion of the variance of language and literacy at age 12, but its predictive ability was overall low and deemed not useful in the clinical setting [ 46 ]. In the neighboring field of speech and voice disorders, the use of genetic information in the clinical setting has also been advocated [ 47 ]. In addition to investigating the direct association between PRS for a relevant trait and developmental outcomes, clinical practice may also benefit, albeit not immediately, from studies into the genetic overlaps across language-related disorders and traits.…”
Section: Introductionmentioning
confidence: 99%