Mejia-Lancheros C et al. riencing homelessness, substance use disorders, incarceration, and sex workers (3). Colombia, with around 50 million inhabitants, is among the countries in the Americas region and the world with the biggest gap between individuals and/or population groups seated at the top (wealthier individuals) and those placed on the bottom of the social and wealth ladder (4). This situation reflects the disparities and inequalities in the Colombian context, which involves not only the economic dimension but also other life dimensions such as educational, social participation, and access to physical and natural resources (5). The country has also experienced significant socio-demographic and epidemiological changes in the last decades. Firstly, there is the demographic transition, with a decrease of the fertility rate from four children in 1980 to less than two children in 2017, and a rise of life expectancy from 65 to 75 years in the last 35 years (6), which has resulted in rapid ageing of the population. Secondly, Colombia is also experiencing a rapid urbanization process, where the population living in an urban area increased from 56.6% in 1970 to Despite the fact that some disease-processes are linked to unmodifiable causes (e.g., biological sex, genetic or inheritable aspects), the health status of individuals and populations is highly dependent on the social, economic and psychosocial environments, the conditions in which people were born, and the experiences over their life-course. These factors are labeled as the social determinants of health (SDoH) or the "causes of the "causes" (1). SDoH include individual factors such as education, place of residence, employment status, income or housing, and aggregated factors such as access to transportation, quality of the health care system, public safety, social cohesion and support, and national and international trade policies (1, 2), which shape, directly and indirectly, the health outcomes and trajectories of individuals. These socioeconomic conditions at individual, neighborhoods, country and global level account for many systematic health (morbidity and mortality) disparities between and within population groups that are unfair and evitable (known as health inequities). The inequalities and injustices due to social conditions are even more pressing and damaging among economically and socially excluded groups, such as poor individuals, of those people expe