Research Article Polymorphisms of the genes <i>eNOS</i>, <i>GSTT1</i> and <i>GSTM1</i> are significantly associated with atherosclerotic disease in hypertensive patients
Abstract:Atherosclerosis is a multifactorial chronic inflammatory disease that occurs in response to endothelial aggression. Systemic arterial hypertension is the main risk factor for the formation of atheromas, increasing the risk of cardiovascular diseases. Several genes are involved in atherogenesis and hypertension. We analyzed polymorphisms of candidate genes that potentially participate in processes related to this pathology, including G894T and T786C of eNOS, as well as GSTT1 and GSTM1 in 167 hypertensive patien… Show more
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