2019
DOI: 10.1111/rssb.12353
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Rerandomization and Regression Adjustment

Abstract: Summary Randomization is a basis for the statistical inference of treatment effects without strong assumptions on the outcome‐generating process. Appropriately using covariates further yields more precise estimators in randomized experiments. R. A. Fisher suggested blocking on discrete covariates in the design stage or conducting analysis of covariance in the analysis stage. We can embed blocking in a wider class of experimental design called rerandomization, and extend the classical analysis of covariance to … Show more

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Cited by 66 publications
(55 citation statements)
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“…While a paired design is often effective at balancing covariates between the treatment and control groups, it may still be helpful to make adjustments for remaining covariate imbalances. Similar situations can occur with other study designs; for example, covariate adjustments may be helpful in rerandomized trials (see Li & Ding, 2020). Perhaps in part because covariate balance is addressed through experimental design, covariate adjustment methods in paired experiments are relatively understudied.…”
Section: Introductionmentioning
confidence: 89%
“…While a paired design is often effective at balancing covariates between the treatment and control groups, it may still be helpful to make adjustments for remaining covariate imbalances. Similar situations can occur with other study designs; for example, covariate adjustments may be helpful in rerandomized trials (see Li & Ding, 2020). Perhaps in part because covariate balance is addressed through experimental design, covariate adjustment methods in paired experiments are relatively understudied.…”
Section: Introductionmentioning
confidence: 89%
“…This result also suggests that the proposed method can also improve the precision of generalizing effect estimation from an RCT to a target population, especially when the outcomes are largely affected by some covariates. Although by randomization these covariates follow the same distribution across the treated and control groups, under finite samples covariate imbalance often occurs due to sampling error (Li and Ding, 2020). The proposed method provides a strategy to tackle such imbalance without resorting to regression adjustment.…”
Section: Theoretical Propertiesmentioning
confidence: 99%
“…More generally, there is a vast literature on using pre-assignment covariates for regression adjustment to increase estimation efficiency [11,13,26,27,30,34]. Our method is based on the augmentation idea of CUPED [6](see also [26]), applied to the one-sided triggering context, and is a general approach that can be used on top of any pre-assignment covariate regression adjustment.…”
Section: Related Workmentioning
confidence: 99%
“…More generally, there is a vast literature on using pre-assignment covariates for regression adjustment to increase estimation efficiency [11,13,26,27,30,34]. Our method is based on the augmentation idea of CUPED [6](see also [26]), applied to the one-sided triggering context, and is a general approach that can be used on top of any pre-assignment covariate regression adjustment. In particular, our approach has the flexibility to incorporate in-experiment observations for covariate adjustment without introducing bias, though there is a tradeoff in the amount of variance reduced.…”
Section: Related Workmentioning
confidence: 99%