Requirement of microtubules for secretion of a micronemal protein CpTSP4 in the invasive stage of the apicomplexanCryptosporidium parvum
Dongqiang Wang,
Peng Jiang,
Xiaodong Wu
et al.
Abstract:The zoonoticCryptosporidium parvumis a global contributor to infantile diarrheal diseases and opportunistic infections in immunocompromised/weakened individuals. Like other apicomplexans, it possesses several specialized secretory organelles, including micronemes, rhoptry and dense granules. However, the understanding of cryptosporidial micronemal composition and secretory pathway remains limited. Here we report a new micronemal protein inC. parvum, namely thrombospondin repeat domain-containing protein-4 (CpT… Show more
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