Reproductive Risk Factors Differ Among Breast Cancer Patients and Controls in a Public Hospital of Paraiba, Northeast Brazil

Almeida, Gibran Sarmento de; Almeida, Layze Amanda Leal; Araujo, Gilmara Marques Rodrigues; Weller, Mathias

doi:10.7314/apjcp.2015.16.7.2959

Cited by 15 publications

(14 citation statements)

References 48 publications

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“…Early menarche, late first full-term pregnancy (after 30 years of age), nulliparity and absence of breastfeeding have also been associated with higher BC risk in Latinas [18,19]. However, their risk impact appears to be lower in Hispanics than non-Hispanics in the US population as 4-Corners Breast Cancer Study found [23].…”

Section: Socioeconomic and Cultural Factorsmentioning

confidence: 90%

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Genetics, tumor features and treatment response of breast cancer in Latinas

Castañeda

Castillo

Villarreal‐Garza

et al. 2018

Breast Cancer Management

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Practice pointsr Latinas with breast cancer have been associated with lower prevalence and higher mortality rates. r The access to healthcare system for Latinas has been described as lower than for white women. r Rates of grade III and triple-negative phenotype breast cancer are higher for Latinas than for white women. r BRCA mutation prevalence appears to be higher in Latinas than white women in the American population. r Distribution of BRCA mutation differs by country in Central, Latin America or Caribbean and recurrent mutations have been described in Mexico. r Finally, evaluated information about treatment efficacy and toxicity in Latinas with breast cancer indicate similar effects than in the white race.Breast cancer is a heterogeneous and genetic disease that has variability according to ethnicity and race with respect to incidence, clinical characteristics and prognosis. The incidence of breast cancer is lower but mortality is higher in Latinas than Caucasians in the US series. Risk factors appear to have different prevalence and impact in Latinas. Breast cancer in Latinas has particular clinic-pathological features including younger age, higher rates of triple-negative subtype and advanced stages. Molecular studies find that Latinas from every region have a specific BRCA incidence and a recurrent mutation, as well as differences in activity of molecular pathways. Treatment response rates and toxicity have also been compared, and no difference was found between Latinas and other ethnic groups.

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Section: Socioeconomic and Cultural Factorsmentioning

confidence: 90%

“…The epidemiologic findings of lower BC incidence and shorter survival in Latinas were also reported for those living in Latin American countries [14][15][16][17][18][19]. However, the incidence appears to be higher in the southern countries of Latin America (Uruguay, Argentina, Chile).…”

mentioning

confidence: 80%

Genetics, tumor features and treatment response of breast cancer in Latinas

Castañeda

Castillo

Villarreal‐Garza

et al. 2018

Breast Cancer Management

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show abstract

“…Risk factors for breast cancer and prevention behaviours have been identified in literature (Almeida et al, 2015;Dey et al, 2015;Paul et al, 2015;Tilaki and Auladi, 2015). To assess knowledge about risk factors and prevention behaviour, women were asked to mark 26 potential risk factors and prevention behaviours.…”

Section: Development and Structure Of The Applied Questionnairementioning

confidence: 99%

Knowledge about Risk Factors for Breast Cancer and Having a Close Relative with Cancer Affect the Frequency of Breast Self-Examination Performance

Freitas

Weller²

2016

Asian Pacific Journal of Cancer Prevention

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“…On the other hand, the prevention of identified modifiable risk factors can be easily propagated in media, as it is relatively inexpensive and may be effective in the long-term. Breastfeeding for example, was identified as a protective factor for BC in a population of North-eastern Brazil and is often propagated as a factor that improves child health, but rarely in the context of BC prevention 17,18 . Furthermore, knowledge about risk factors that women cannot change in a given phase of their life such as age, age at first gestation or menopause status, could encourage their participation on BC screening programs.…”

Section: Final Considerationsmentioning

confidence: 99%

“…In Brazil for example, the Latin American country with the largest population, prevention strategy of BC are mainly focused on ED and so far, there is no public information campaign about risk factors 17 . A recent study identified breastfeeding as a protective factor in a population of North-eastern Brazil 18 . In this region, BC mortality rate increased 5.3% annually during the last decade 19 .…”

Section: Introductionmentioning

confidence: 99%