Reproductive outcomes after in-vitro fertilization

Mukhopadhaya, Neelanjana; Arulkumaran, Sabaratnam

doi:10.1097/gco.0b013e32807fb199

Cited by 43 publications

(37 citation statements)

References 53 publications

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“…In a systematic review [21], Shevell et al [3] found that increased maternal complications such as 6 fold high increased placenta previa, 1.6 fold high gestational hypertension, 0.5 fold higher gestational diabetes, 2.4 fold high placental abruption, 2 fold higher caesarean delivery rates. Kallen et al [22] and Romundstad et al [23] found increased placenta previa rates in IVF cycles than naturally conceived pregnancies, 4 fold and 6 fold higher respectively.…”

Section: Discussionmentioning

confidence: 99%

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Cakar

Yavuz

Kutlu

et al. 2018

ijmsci

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ABSTRACT:Background: We aimed to compare perinatal outcomes of intracytoplasmicsperm injection (ICSI) versus naturally (spontaneously) concieved age and parity matched group of singleton pregnants. Methods: Two hundred and sixteen singleton pregnancies aged between 18-45 years old were included in this study. Among all study group, 106 cases were ICSI pregnancies (study group) and 110 cases were spontaneously concieved singleton pregnancies (control group). Pregnancy outcome parameters were: the incidence of chronic hypertension, preeclampsia, gestational hypertension, placenta previa, placental abruption, preterm birth, intrahepatic cholestasis of pregnancy, gestational diabetes, preterm premature rupture of membranes, caesarean delivery. Results: There were no differences in terms of maternal age, BMI, gravidity, parity, gestational weeks at birth and birth weight between ICSI and spontaneously concieved pregnancy groups. Placental abruption, gestational diabetes and cesarean section rates were significantly higher in ICSI pregnancies than spontaneously conceived pregnancies (4.7% vs 0%, 21.7% vs 11.8% and 82.1% vs 68.2%, respectively). There wereno statistically significant differences in terms of chronic hypertension, preeclampsia, gestational hypertension, preterm labor, placenta previa, intrahepatic cholestasis of pregnancy, preterm and term premature rupture of the membranes. Conclusion: ICSI pregnancies have higher adverse perinatal outcomes than spontaneously conceived singleton pregnancies which were matched with age and parity. That's why ICSI pregnancies should be given a detailed counseling about the adverse perinatal outcomes and should be followed up more carefully through the pregnancy.

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Section: Discussionmentioning

confidence: 99%

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Cakar

Yavuz

Kutlu

et al. 2018

ijmsci

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“…First, because we included only singleton births, our findings may not be applicable to multi-fetal pregnancies, whose maternal and perinatal risk factors and outcomes can differ from those of singleton pregnancies. 25 All of the maternal variables we found to be associated with maternal and neonatal ICU admission, except for hospital admission in the preceding year, were captured in the index hospital admission. Hence, the effects of pre-existing maternal comorbidities could not be distinguished from those arising at the time of, or soon after, ICU admission.…”

Section: Strengths and Limitationsmentioning

confidence: 94%

Maternal and neonatal separation and mortality associated with concurrent admissions to intensive care units

Ray

Urquia

Berger

et al. 2012

CMAJ

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“…are linked with the couple's underlying infertility factors, medical factors, maternal age, obesity or the ART processes themselves (Mukhopadhaya & Arulkumaran, 2007). For example, Chen et al (2009) in their retrospective Canadian study found that pre-eclampsia occurred more frequently in women who had conceived through IVF than in women who had conceived through two other ARTs: ovulation induction or intrauterine insemination.…”

mentioning

confidence: 99%

“…Furthermore, a two fold increase in gestational diabetes mellitus is seen in women undergoing ART, which may be associated with the underlying cause of infertility, e.g. polycystic ovarian syndrome (Mukhopadhaya & Arulkumaran, 2007).…”

mentioning

confidence: 99%

Reflections on evolution

Gunn¹

2013

nzcomjnl

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Reproductive outcomes after in-vitro fertilization

Cited by 43 publications

References 53 publications

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital

Maternal and neonatal separation and mortality associated with concurrent admissions to intensive care units

Reflections on evolution

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