Reproductive outcomes after bariatric surgery in women

Micić, Dragan; Toplak, Hermann; Mićić, Dragan; Polovina, Snežana

doi:10.1007/s00508-021-01986-w

Cited by 12 publications

(9 citation statements)

References 63 publications

(84 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bariatric surgery is an invasive procedure, and will cause a delay in fertility treatment because it is undesirable to conceive during a period of rapid weight loss. Furthermore, pregnancy complications due to nutrient malabsorption after bariatric surgery are also possible [ 1 , 38 ]. Other less invasive options, such as the use of insulin sensitizers like metformin or thiazolidinediones, are proven to be beneficial for weight loss and the treatment of infertility in women with PCOS [ 39 ].…”

Section: Discussionmentioning

confidence: 99%

Pregnancy Outcomes in Women with PCOS: Follow-Up Study of a Randomized Controlled Three-Component Lifestyle Intervention

Loos

Jiskoot

Louwers

et al. 2023

JCM

View full text Add to dashboard Cite

Women with polycystic ovary syndrome (PCOS) and excess weight often present with reproductive derangements. The first-line treatment for this population is a multi-component lifestyle intervention. This follow-up study of a randomized controlled trial based on data from the Dutch Perinatal registry was conducted to study the effect of a one-year three-component (cognitive behavioral therapy, healthy diet, and exercise) lifestyle intervention on pregnancy outcomes in women with PCOS and overweight or obesity. Women diagnosed with PCOS, a BMI ≥ 25 kg/m², and a wish to conceive were randomized to either three-component lifestyle intervention (LSI, n = 123), and care as usual (CAU, n = 60) where they were encouraged to lose weight autonomously. Conception resulting in live birth was 39.8% (49/123) within LSI and 38.3% (23/60) within CAU (p = 0.845). In total, 58.3% conceived spontaneously. Gestational diabetes (LSI: 8.2% vs. CAU: 21.7%, p = 0.133), hypertensive disorders (LSI: 8.2% vs. CAU 13.0%, p = 0.673), and preterm birth (LSI: 12.2% vs. CAU: 17.4%, p = 0.716) rates were all lower in LSI compared to CAU. This follow-up study showed no significant differences in conception resulting in live birth rates between LSI and CAU. Nonetheless, a large proportion eventually conceived spontaneously. Moreover, after LSI, the number of uneventful pregnancies was lower compared to care as usual.

show abstract

Section: Discussionmentioning

confidence: 99%

Pregnancy Outcomes in Women with PCOS: Follow-Up Study of a Randomized Controlled Three-Component Lifestyle Intervention

Loos

Jiskoot

Louwers

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

“…This genomic region may be selected to improve the reproduction performance of Jinhua pigs. Obesity is closely related to reproduction and fertility, such as embryonic development ( 65 ) and spermatogenesis ( 66 ) through various mechanisms. Low BFT is an important breeding objective for Duroc pigs, and animals carrying this adverse ROH showed higher BFT values than Non-carriers.…”

Section: Discussionmentioning

confidence: 99%

Identification of Homozygous Regions With Adverse Effects on the Five Economic Traits of Duroc Pigs

Wang

Yang

et al. 2022

Front. Vet. Sci.

View full text Add to dashboard Cite

Runs of homozygosity (ROH) are widely used to estimate genomic inbreeding, which is linked to inbreeding depression on phenotypes. However, the adverse effects of specific homozygous regions on phenotypic characteristics are rarely studied in livestock. In this study, the 50 K SNP data of 3,770 S21 Duroc (American origin) and 2,096 S22 Duroc (Canadian origin) pigs were used to investigate the harmful ROH regions on five economic traits. The results showed that the two Duroc lines had different numbers and distributions of unfavorable ROHs, which may be related to the different selection directions and intensities between the two lines. A total of 114 and 58 ROH segments were found with significant adverse effects on the economic traits of S21 and S22 pigs, respectively. Serval pleiotropic ROHs were detected to reduce two or multiple phenotypic performances in two Duroc populations. Candidate genes in these shared regions were mainly related to growth, fertility, immunity, and fat deposition. We also observed that some ROH genotypes may cause opposite effects on different traits. This study not only enhances our understanding of the adverse effects of ROH on phenotypes, but also indicates that ROH information could be incorporated into breeding programs to estimate and control the detrimental effects of homozygous regions.

show abstract

“…Guidelines from the American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic and Bariatric Surgery recommend that pregnancy be delayed until 12 to 18 months postprocedure to allow for weight stabilization and then, when pregnant, optimal nutrition for fetal growth. 30 Fertility indicators improve 31 and women generally show an increase in sexual activity postsurgery. 32 However, a retrospective cohort study indicated that only around 55% of those who underwent bariatric surgery and were at risk of pregnancy had documented use of contraception postsurgery.…”

Section: Weight Managementmentioning

confidence: 99%

Best Practice Contraception Care for Women with Obesity: A Review of Current Evidence

McNamee

Edelman

et al. 2022

Semin Reprod Med

View full text Add to dashboard Cite

The prevalence of obesity among females of reproductive age is increasing globally. Access to the complete range of appropriate contraceptive options is essential for upholding the reproductive rights of this population group. People with obesity can experience stigma and discrimination when seeking healthcare, and despite limited evidence for provider bias in the context of contraception, awareness for its potential at an individual provider and health systems level is essential. While use of some hormonal contraceptives may be restricted due to increased health risks in people with obesity, some methods provide noncontraceptive benefits including a reduced risk of endometrial cancer and a reduction in heavy menstrual bleeding which are more prevalent among individuals with obesity. In addition to examining systems-based approaches which facilitate the provision of inclusive contraceptive care, including long-acting reversible contraceptives which require procedural considerations, this article reviews current evidence on method-specific advantages and disadvantages for people with obesity to guide practice and policy.

show abstract

Reproductive outcomes after bariatric surgery in women

Cited by 12 publications

References 63 publications

Pregnancy Outcomes in Women with PCOS: Follow-Up Study of a Randomized Controlled Three-Component Lifestyle Intervention

Pregnancy Outcomes in Women with PCOS: Follow-Up Study of a Randomized Controlled Three-Component Lifestyle Intervention

Identification of Homozygous Regions With Adverse Effects on the Five Economic Traits of Duroc Pigs

Best Practice Contraception Care for Women with Obesity: A Review of Current Evidence

Contact Info

Product

Resources

About