Reproductive outcome of septate uterus after hysteroscopic metroplasty

Abstract

We evaluated the reproductive outcome after hysteroscopic metroplasty in the patients with septate uterus. The reproductive performance of 361 patients with septate uterus during the follow-up period of 18 months after the surgery was analyzed retrospectively for a period of 10 years. A total of 180 (49.8%) pregnancies were achieved after metroplasty during the follow-up period of 18 months. Of the 180 pregnancies 117 (57.2%) reached to term and 34 (18.8%) ended in preterm delivery and the remaining 29 (16%) resulted in abortion. Of the preterm babies 18 (52.9%) were able to live. We obtained 135 (75%) live babies totally. Hysteroscopic metroplasty improves the reproductive performance of septate uterus significantly especially in the cases with recurrent pregnancy loss and should be considered highly as a corrective approach for such patients.

Hysteroscopic metroplasty in patients with a uterine septum and otherwise unexplained infertility

“…For example, Fedele et al [9] reported a 3‐year cumulative pregnancy rate of 39% in the infertile patient group and 62% in the abortion group; however, there were additional factors that might have caused infertility in 13 of the 31 infertile patients in that study. Saygili et al [19] found an 18‐month cumulative pregnancy rate of 23.3% in the infertile group and 83.1% in the habitual abortion group. In addition, Litta et al [20] reported a term pregnancy rate of 83% in patients with 1 or more abortion, and 53.3% in the infertile group [20].…”

Hysteroscopy may be justified after two miscarriages

“…Studies have shown that hysteroscopic resection of the septum in a septate uterus improves pregnancy outcome in subsequent pregnancies in women with recurrent miscarriages (Porcu et al, 2000;Saygili-Yilmaz et al, 2003;Valli et al, 2004). Hysteroscopic adhesiolysis also improves pregnancy outcome in women with recurrent miscarriages (Goldenberg et al, 1995;Katz et al, 1996).…”

Laparoscopic metroplasty in bicornuate and didelphic uteri

“…Patients with M€ ullerian duct anomalies are known to have a higher incidence of infertility, repeating first trimester spontaneous abortion, intrauterine fetal growth retardation, fetal malposition, preterm labor, and retained placenta (1,2). The mean prevalence of these anomalies in the infertile women is 3.5%, and in women with recurrent abortion it is 13% (3).…”