Reproductive Factors and Risk of Spontaneous Abortion in the Jinchang Cohort

Hu, Xiaobin; Miao, Miao; Bai, Yana; Cheng, Ning; Ren, Xiaowei

doi:10.3390/ijerph15112444

Cited by 29 publications

(27 citation statements)

References 20 publications

(15 reference statements)

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“…A study indicates that recurrence risk of NTDs was around 1–3% [ 29 ]. Moreover, when the fetus is affected by congenital abnormality like NTDs could end with spontaneous abortion [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

Risk factors associated to neural tube defects among mothers who gave birth in North Shoa Zone Hospitals, Amhara Region, Ethiopia 2020: Case control study

Gashaw¹,

Shine

Yimer

et al. 2021

PLoS ONE

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Introduction Neural tube defects affect the brain and the spinal cord of the developing embryo. The defects occur due to incomplete or failure of closure of the neural tube. The condition eventually causes death and lifelong disability. Worldwide, more than 300,000 babies are born with neural tube defects each year. The highest burden is in low- and middle-income countries. Therefore, this study aims to identify the risk factors associated with neural tube defects among mothers who gave birth in North Shoa Zone Hospitals. Methods A hospital based unmatched case-control study was conducted among 243 (81 cases and 162 controls) study participants in North Shoa Zone Hospitals. The hospitals were selected using simple random sampling and all cases and randomly selected controls in the selected hospitals were included in the study. The data were collected by using pre-tested structured questionnaire. Results Different factors were identified to have association with neural tube defect. Family annual cash income less than 24000ETB (AOR: 3.73, 95%CI: 1.35, 10.26), history of still birth (AOR: 3.63, 95%CI: 1.03, 12.2), history of abortion (AOR: 6.15, 95%CI: 2.63, 18.56), preconception tea use (AOR: 2.36, 95%CI: 1.15, 4.86) and pesticides/chemical exposure (AOR: 5.34, 95%CI: 1.77, 16.05) were positively associated factors. In contrast, preconception care (AOR: 0.14, 95%CI: 0.05, 0.39) and taking iron/folic acid/multivitamin during the current pregnancy (AOR: 0.16, 95%CI: 0.07, 0.33) showed a protective effect. Conclusion Family annual income less than 24000ETB, history of still birth, history of abortion, preconception tea uses and pesticides/chemical exposure were associated factors of neural tube defects. Preconception counseling and screening should be recommended for women who plan for pregnancy.

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Section: Discussionmentioning

confidence: 99%

Risk factors associated to neural tube defects among mothers who gave birth in North Shoa Zone Hospitals, Amhara Region, Ethiopia 2020: Case control study

Gashaw¹,

Shine

Yimer

et al. 2021

PLoS ONE

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“…El principal resultado del presente estudio fue una ocurrencia del aborto espontáneo en 7,25 % de la población. Algunos estudios que han reportado este fenómeno muestran cifras similares (11)(12)(13). En China, en mujeres en edad fértil, se ha reportado que este fenómeno ocurrió en el 6,89 % de las mujeres embarazadas (11).…”

Section: Discussionunclassified

“…Algunos estudios que han reportado este fenómeno muestran cifras similares (11)(12)(13). En China, en mujeres en edad fértil, se ha reportado que este fenómeno ocurrió en el 6,89 % de las mujeres embarazadas (11). En Dinamarca, un estudio de cohortes reportó que en el 3,47 % de embarazos terminaban con abortos espontáneos (12).…”

Section: Discussionunclassified

“…En el grupo estudiado se encontró que, al estimar la asociación entre la edad y el fenómeno estudiado, existía una relación inversa (RP 0,93 IC 95 % 0,77-1,12): se parte de la hipótesis de que, debido a que el grupo de edad estudiado oscila entre 18 y 28 años, no existe la suficiente variabilidad para que genere resultados similares a diferentes reportes en los que la edad es un factor importante en esta (11,12,(17)(18)(19). Por ejemplo, Hu et al (11) reportó que en una muestra de 18 000 mujeres chinas el riesgo de aborto espontáneo aumenta de manera proporcional con la edad. En la misma línea, varios reportes han mostrado que, a medida que aumenta la edad, hay mayor riesgo (12,17,18); otros reportes han descrito que el efecto de la edad del padre ha mostrado la misma relación (19).…”

Section: Discussionunclassified

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Aborto espontáneo en estudiantes universitarias en Pamplona, Norte de Santander, en el periodo del año 2007 al 2016. Un estudio transversal

Malpica

Flórez

Martínez-Torres

et al. 2021

Revista Investig. Salud Univ. Boyacá

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Introducción: El aborto espontáneo se refiere al fenómeno por el cual un embrión o feto se descarga automáticamente del cuerpo de la madre por alguna razón involuntaria, generalmente a las 20 semanas del embarazo. Entre el 15 % y el 20 % de todos los embarazos tienen riesgo de aborto espontáneo, alrededor de un 10 % terminarán siendo abortos espontáneos. Metodología: Estudio descriptivo transversal con intención analítica. Se tomaron los datos de 207 historias clínicas del archivo del hospital público de Pamplona, Norte de Santander, de mujeres gestantes universitarias, correspondientes a los periodos del año 2007 al 2016. Se consideró aborto espontáneo la variable reportada en la historia clínica. Se estimó la frecuencia de aborto espontáneo y se exploró la asociación con diferentes variables clínicas y sociodemográficas en estudiantes universitarias. Se construyeron modelos de regresión binomial simple y multivariable, para estimar la asociación entre las variables. Resultados: Se reportaron 15 abortos espontáneos (7,5 %), aquellas que no se habían aplicado la vacuna antitetánica y quienes no se realizaron citología durante los 12 meses previos presentaron los mayores porcentajes de abortos espontáneos (16,7 % y 15,2 %, respectivamente). Las mujeres que acusaron haber estado hospitalizadas (RP 4,01 IC 95 % 1,69-9,49), y haber tenido abortos previamente (RP 7,53 IC 95 % 3,02-18,77), mostraron asociación con el aborto espontáneo. Conclusión: Se pudo estimar que la proporción de abortos espontáneos es similar a lo reportado en otros estudios; no obstante, es necesario generar investigaciones adicionales que evalúen la relación entre el aborto espontáneo y factores individuales y contextuales para generar estrategias que disminuyan estas cifras.

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“…This is a very restrictive assumption of the SPR model that the conditional mean equals the conditional variance. To test this assumption, the increase in variance is represented in the model by a constant multiple of the variance-covariance matrix as [10], [11]:…”

Section: A Model Specificationmentioning

confidence: 99%

Statistical Challenges of The Sustainable Development in Iraq

Hussain¹

2020

Int. J. Adv. Sci. Eng. Inf. Technol.

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Many challenges on the road to sustainable development face Iraq. Data limitations cause massive constraints on sustainable development goals checking because about 70% of indicators are missing in Iraq. Statistical indicators are considered as the basis of sustainable development in each country. The healthy population was the third goal of sustainable goals because the healthy population produces a high level of sustainable development. Consequently, fertility is an important indicator of a healthy population because it is one of the three principal components of population dynamics that increases the size of any country's population. The important indicator of fertility is the number of newborns for the married women. Therefore, the problem of this research is about 70% of sustainable development goals indicators currently are missing in Iraq, especially inferential indicators including modelling of the association between the phenomena and their risk factors. Then the goal of this research is to build a model to represent the association between the fertility and its risk factors to provide an inferential indicator about this phenomenon to identify the most influential risk factors. Several risk factors are facing the pregnancy before childbirth, but what are the most influential risk factors cause it? The count regression models are a statistical technique may be used to express the association between the number of fertility and its risk factors. A simple random sample was drawn with size (200) consists of the mothers who visit the primary health care centres in Babylon province-Iraq in year 2018. Biological, behavioural and lifestyle factors are recorded. The results of applying Poisson regression model show that the data was overdispersion, with nonlinear function and with number of outliers. Therefore, the nonparametric Poisson model was used as an alternative model to this data. The results of applying this model show that the most influential risk factors are five linear risk factors in addition to three nonparametric smoothing factors.

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Reproductive Factors and Risk of Spontaneous Abortion in the Jinchang Cohort

Cited by 29 publications

References 20 publications

Risk factors associated to neural tube defects among mothers who gave birth in North Shoa Zone Hospitals, Amhara Region, Ethiopia 2020: Case control study

Risk factors associated to neural tube defects among mothers who gave birth in North Shoa Zone Hospitals, Amhara Region, Ethiopia 2020: Case control study

Aborto espontáneo en estudiantes universitarias en Pamplona, Norte de Santander, en el periodo del año 2007 al 2016. Un estudio transversal

Statistical Challenges of The Sustainable Development in Iraq

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