Reproductive disorders due to chemical exposure among hairdressers

Kersemaekers, WM; Roeleveld, Nel; Zielhuis, Gerhard A.

doi:10.5271/sjweh.46

Cited by 57 publications

(48 citation statements)

References 41 publications

(12 reference statements)

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“…Reproductive disorders, including spontaneous abortions (31,32) and major malformations (32), have previously been observed among hairdressers, but not to a statistically significant degree. It has been suggested that these effects are related to several specific chemicals to which this occupational group is exposed (33). A few studies have associated housekeeping workers with an increased risk of oral clefts (21,34).…”

Section: Discussionmentioning

confidence: 99%

Maternal occupational risk factors for oral clefts

Lorente

Cordier

Bergeret

et al. 2000

Scand J Work Environ Health

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Objectives This study investigated the role of maternal exposures at work during pregnancy in the occurrence of oral clefts. MethodsThe occupational exposures of 851 women (100 mothers of babies with oral clefts and 751 mothers of healthy referents) who worked during the first trimester of pregnancy were studied. All the women were part of a multicenter European case-referent study conducted using 6 congenital malfolmation registers between 1989 and 1992. In each center, the mother's occupational histoty, obtained from an interview, was reviewed by industrial hygienists who were blinded to the subject's status and who assessed the presence of chemicals and the probability of exposure. Odds ratios (OR) were estimated by a multivariate analysis including maternal occupation or occupational exposures during the first trimester of pregnancy and possible confounding factors such as center of recruitment, maternal age, urbanization, socioeconomic status, and country of origin.Results After adjustment for confounding factors, cleft palate only was significantly associated with maternal occupation in services such as hairdressing [OR 5.1,95% confidence interval (95% CI) 1.0-26.01 and housekeeping (OR 2.8,95% CI 1.1-7.2). The analysis suggests that the following occupational exposures are associated with orofacial clefts: aliphatic aldehydes (OR 2.1,95% CI 0.8-5.9) and glycol ethers (OR 1.7,95% CI 0.9-3.3) for cleft lip with or without cleft palate and lead compounds (OR 4.0,95% CI 1.3-12.2), biocides (OR 2.5,95% CI 1.0-6.0), antineoplastic drugs (OR 5.0,95% CI 0.8-34.0), trichloroethylene (OR 6.7,95% CI 0.949.7), and aliphatic acids (OR 6.0,95% CI 1.5-22.8) for cleft palate only. C O~C I U S~O~SDue to the limited number of subjects, these results must be interpreted with caution. However, they point out some chemicals already known or suspected as reproductive toxins. [E-mail: lorente@vjf.inserm.fr] multifactorial in origin and are caused by both genetic and environmental factors. Many genetic (risk of Scand J Work Environ Health 2000, vol26, no 2 Key terms 137in Europe (1). Investigators agree that oral clefts are recurrence) and epidemiologic (sex ratio, prevalence)

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Section: Discussionmentioning

confidence: 99%

Maternal occupational risk factors for oral clefts

Lorente

Cordier

Bergeret

et al. 2000

Scand J Work Environ Health

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“…Kersemaekers et al (1995) evaluated reproductive disorders due to chemical exposure among hairdressers to determine risk and identify the activities and agents most likely to cause such effects. They found inconsistent results from epidemiologic studies and limited human data on the reproductive risks of chemicals and chemical amounts used in salons, leading to few data-driven conclusions (Kersemaekers et al, 1995).…”

Section: Relevant Studies Of Reproductive Hazardsmentioning

confidence: 99%

“…They found inconsistent results from epidemiologic studies and limited human data on the reproductive risks of chemicals and chemical amounts used in salons, leading to few data-driven conclusions (Kersemaekers et al, 1995). Axmon, Rylander, Lillienberg, Albin, and Hagmar (2006) found prolonged “time-to-pregnancy” among hairdressers.…”

Section: Relevant Studies Of Reproductive Hazardsmentioning

confidence: 99%

“…Regarding carcinogenicity, the primary concern is chemical absorption through human skin (McCall et al, 2005). However, the level of absorption depends on the extent of dermal contact (Kersemaekers et al, 1995). Hair dyes are found in many forms (i.e., liquids, creams, gels, shampoos, and rinses), and the method of application may affect exposure.…”

Section: Mechanisms Of Actionmentioning

confidence: 99%

“…Because the chemical environment in salons has changed over time, reproductive risks that were present in earlier years may have changed as well (Kersemaekers et al, 1995). New molecular epidemiological and longitudinal studies are needed to investigate developmental and reproductive toxicity in females to better understand the effects of formaldehyde (Duong et al, 2011) and other chemicals present in hair dye and nail polish.…”

Section: Future Directions and Implications For Occupational Health Nmentioning

confidence: 99%

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Occupational Chemical Exposures Among Cosmetologists: Risk of Reproductive Disorders

2013

Workplace Health Saf

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More research is needed to understand possible occupational reproductive risks for cosmetologists, specifically hairdressers and nail technicians, two occupations that often share workspace and exposure to hair dyes and nail polish. Cosmetologists are predominantly females of reproductive age; thus, they may be at higher risk for the effects of exposure to reproductive toxins. The purpose of this article is to inform nurses and public health professionals about occupational exposures for cosmetologists and discuss interventions to reduce the risks of reproductive disorders among susceptible worker populations.

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Aromatic Amino and Nitro–Amino Compounds and Their Halogenated Derivatives

Darby

2023

Patty's Toxicology

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The fundamental aromatic hydrocarbon benzene, when substituted by one or more functional groups of the amine, nitro, or halogen classes, alone or in various combinations, provides an enormous number of compounds of immense practical value, ubiquitous presence in the industrial world, and often heightened toxicity relative to benzene itself, a notorious cause of blood cancer. This chapter begins by providing a general overview of aromatic compounds possessing amino and/or nitro substituents, with or without halogen substituents. The production and uses, exposure and biomonitoring, toxicity, and toxic mechanism of action are introduced. The remainder of the chapter focuses on specific compounds in a roughly systematic order based upon chemical structure, expanding on the same subheadings as covered in the general overview. The nomenclature of these compounds can be very confusing since many have traditional names that sometimes markedly differ from their systematized formal names. In this chapter, the same traditional names are used as were used in the previous edition of this publication, but if there is ambiguity of nomenclature, the Chemical Abstracts Service (CAS) numbers provided herein correspond to unique structures, each of which may have several names depending upon the naming convention. In general, when an aromatic compound has an amino or a nitro substituent, it is referred to as an “aniline” or a “nitrobenzene,” respectively, based upon the names of the parent compounds, even though other substituents may be present. When amino and nitro groups are present on the same benzene ring, “aniline” takes precedence, and both “aniline” and “nitrobenzene” take precedence over halogens. There are many exceptions to these general rules, however.

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Reproductive disorders due to chemical exposure among hairdressers

Cited by 57 publications

References 41 publications

Maternal occupational risk factors for oral clefts

Maternal occupational risk factors for oral clefts

Occupational Chemical Exposures Among Cosmetologists: Risk of Reproductive Disorders

Aromatic Amino and Nitro–Amino Compounds and Their Halogenated Derivatives

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