Reproductive Disorders and Seroprevalence of Brucellosis in Yak

Aryal, Sitaram; Paudel, Krishna P.

doi:10.3126/narj.v8i0.11608

Cited by 7 publications

(5 citation statements)

References 4 publications

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“…In this study the seroprevalence of brucellosis in pregnant women was found to be 11.25%. Previously, it was reported that the seroprevalence of human brucellosis in Kathmandu was 11.95% [12]. Similarly, it was reported as 20% in Surkhet district and 14% in the patients visiting Bir hospital [13].…”

Section: Discussionmentioning

confidence: 99%

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Sero Prevalence of Brucellosis in Pregnant Women Visiting Gynaecology Department of Kathmandu Model Hospital, Kathmandu, Nepal

Thapa¹,

Maharjan²

2018

Natl. j. health sci.

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Introduction: Brucellosis is a highly contagious zoonotic disease caused by ingestion of unpasteurized milk or undercooked meat from infected animals or close contact with their secretions. Subject and Methods:Sero-prevalence of brucellosis in pregnant women was conducted for the first time in Kathmandu, Nepal. A total of 80 sera samples were collected from the pregnant women visiting Kathmandu Model Hospital. The patients were categorized on the basis of age, trimester and ethnic groups. The sera samples were tested by ELISA method. Results:The sero-prevalence of brucellosis among pregnant women was found to be 11.25%. Madhesi ethnic group showed the highest (16.66%) seropositivity rates followed by Janajati (11.53%) and the lowest was in Brahmin (8.33%) ethnic group. Similarly, the age group 31-35 years showed highest prevalence (29.41%) followed by the age group 26-30 years (13.33%). There is absence of seropositivity among the age group 16-20 years and 21-25 years. The highest sero-prevalence rate (12.76%) was found in the third trimester followed by first trimester (10%) and the lowest was in second trimester (8.69%). About 3% of them consume raw milk directly from milking animals which is one of the risk factor of brucellosis in pregnant women. Conclusion:The prevalence was found to be high in pregnant women and ELISA was a sensitive and specific test for the detection of IgG antibodies against Brucella.

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Section: Discussionmentioning

confidence: 99%

“…The seroprevalence of brucellosis was high (2.72%) among the people above 50 years age group in Chitwan [16], 20-29 years (29%) in Surkhet [13] and 6-15 years age group (29.17% ) in Kathmandu [12].…”

Section: Discussionmentioning

confidence: 99%

Sero Prevalence of Brucellosis in Pregnant Women Visiting Gynaecology Department of Kathmandu Model Hospital, Kathmandu, Nepal

Thapa¹,

Maharjan²

2018

Natl. j. health sci.

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“…Although brucellosis has been reported to be endemic in Nepal, neither the distribution nor the economic and public health impact of this disease is well characterized [ 44 , 46 ]. Robust and well-designed nationwide survey is warranted to assess the prevalence and distribution of disease in livestock and humans.…”

Section: Main Bodymentioning

confidence: 99%

Overview of Brucellosis in Nepal

Acharya¹,

Niroula²,

Kaphle³

2016

Epidemiol Health

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OBJECTIVESThe aim of this paper is to evaluate the current status of the disease, the mechanism of infection, and pathogenesis, its zoonotic potential, diagnostic advances, treatment regimens, and the preventive measures that can be adopted in managing human brucellosis in under-developed countries such as Nepal. METHODSWe performed a systematic review of all the available literture through Google Scholar, PubMed, Gideon Informatics, World Health Organization and other legitimate sources. Other secondary informations were collected from the government agencies such as department of livestock services and Ministry of Health. The obtained information was then re-analysed and summarized. RESULTSFew publications have addressed brucellosis in Nepal and most of those publications have focused on bovine brucellosis with sparse information available on brucellosis in humans and small ruminants. Brucella abortus is the most predominant causative agent followed by B. suis. B. abortus is predominant in cattle accounting for a substantial portion of bovine abortion in the country. Lack of awareness, unhealthy food habit, traditional husbandry practices, and a lack of surveillance and immunization have been the major factors in maintaining a vicious cycle of propagation of the disease in human and animals. Unfortunately, nothing has been done to identify the species of Brucella at the biovar level. CONCLUSIONSAlthough brucellosis has been reported to be endemic in Nepal, neither the distribution nor the economic and public health impact of this disease is well characterized. Robust and well-designed nationwide survey is warranted to assess the prevalence and distribution of disease in livestock and humans. Such data would facilitate the design of appropriate control programmes.

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“…Although there are some published studies describing the seroprevalence of animal and human brucellosis in Nepal [24][25][26], there are no studies that describe the risk factors related to animal brucellosis in Nepal. Identifying risk factors and implementing prevention and control programs could lead to a decrease in the disease burden in small ruminants, with consequent improvements in human health.…”

Section: Introductionmentioning

confidence: 99%

Sero-epidemiology and associated risk factors of brucellosis among sheep and goat population in the south western Nepal: a comparative study

Gompo¹,

Shah

Tiwari

et al. 2021

BMC Vet Res

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Background Brucellosis is a zoonotic disease caused by Brucella spp. In Nepal, the presence of brucellosis in small ruminants, namely sheep and goats, has impacted farmers’ livelihood and the food safety of consumers. A cross-sectional study was conducted in Rupandehi district of Nepal during January to March 2020 to investigate the seroepidemiology and associated risk factors of brucellosis in the sheep and goat population. Altogether, 19 sheep and 60 goat farms in the district were visited. Owners were interviewed to get information on animals, including their management and movement patterns. Three hundred fifty-seven samples (80 sheep and 277 goat samples) were collected proportionately based on farm sizes. Each serum sample was tested with Rose Bengal Test and ELISA to estimate the seropositivity of brucellosis. Logistic regression was carried out to calculate corresponding odds ratios of each variable associated with detection of brucellosis. Results At the farm level, 31.6% (6/19; 95% CI: 12, 54%) of sheep farms and 3.3% (2/60, 95% CI: 0.9, 11.4%) of goat farms were seropositive to brucellosis. Out of 80 sheep serum samples, 12 (15%; 95% CI: 8.79–24.41%) and out of 277 goat serum samples, three (1.1%; 95% CI: 0.37–3.14%) were seropositive to brucellosis. Age greater than 1.5 years (OR = 5.56, 95% CI: 1.39, 29.38; p = 0.02) and herd size of greater than 100 (OR = 4.74, 95% CI: 1.23, 20.32, p = 0.03) were identified as significant risk factors for seropositivity of brucellosis in the sheep population. While in the goat population, none of the variables was identified as a significant risk factor. Conclusion The study provides evidence that the older sheep and the sheep from the large herds were at higher risk of brucellosis. A control program should be put in place immediately in the sheep population because they may transmit infections to other livestock as they were regularly moved for grazing and selling purposes. Also, strict biosecurity measures should be implemented among pastoralists to prevent brucellosis transmission in them. We suggest further one health-based study to reveal the transmission dynamics of brucellosis between animals and humans.

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Reproductive Disorders and Seroprevalence of Brucellosis in Yak

Cited by 7 publications

References 4 publications

Sero Prevalence of Brucellosis in Pregnant Women Visiting Gynaecology Department of Kathmandu Model Hospital, Kathmandu, Nepal

Sero Prevalence of Brucellosis in Pregnant Women Visiting Gynaecology Department of Kathmandu Model Hospital, Kathmandu, Nepal

Overview of Brucellosis in Nepal

Sero-epidemiology and associated risk factors of brucellosis among sheep and goat population in the south western Nepal: a comparative study

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